nectin2.L nectin cell adhesion molecule 2 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: nectin2.L
Official Full Name: nectin cell adhesion molecule 2 L homeolog
Primary source: Xenbase:XB-GENE-947435
Locus tag: XELAEV_18036021mg
See related: EnsemblRapid:ENSXLAG00005021769
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ed4; prr; higr; hveb; hvec; ofc7; prr1; prr2; pvrr; cd111; cd112; pvrl1; pvrl2; pvrr1; pvrr2; sk-12; clped1; pvrl2.L; nectin-1; nectin-2
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 7L

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7L	NC_054383.1 (114826968..114858438)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7L	NC_030736.1 (104296840..104328403)

Chromosome 7L - NC_054383.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables cell adhesion molecule binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within acrosome assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within coreceptor-mediated virion attachment to host cell	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cytoskeleton organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within establishment of mitochondrion localization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within fusion of virus membrane with host plasma membrane	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of T cell receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of immunoglobulin mediated immune response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of mast cell activation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of viral entry into host cell	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within susceptibility to T cell mediated cytotoxicity	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within susceptibility to natural killer cell mediated cytotoxicity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in apical junction complex	IEA Inferred from Electronic Annotation more info
located_in extracellular exosome	IEA Inferred from Electronic Annotation more info
located_in focal adhesion	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: nectin cell adhesion molecule 2 L homeolog

Names: nectin 2; nectin-2alpha; poliovirus receptor-related 1 (herpesvirus entry mediator C); poliovirus receptor-related 2 (herpesvirus entry mediator B) L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094175.1 → NP_001087644.1 nectin cell adhesion molecule 2 L homeolog precursor

See identical proteins and their annotated locations for NP_001087644.1

Status: PROVISIONAL

Source sequence(s)

BC081035

UniProtKB/TrEMBL

A0A974CGT6, Q66J72

Related

ENSXLAP00005063944.1, ENSXLAT00005065458.1

Conserved Domains (4) summary

cd05718
Location:32 → 122

Ig1_PVR_like; First immunoglobulin (Ig) domain of poliovirus receptor (PVR, also known as CD155) and similar proteins

cd07703
Location:125 → 217

Ig2_Nectin-2_like; Second immunoglobulin (Ig) domain of nectin-2 (also known as poliovirus receptor related protein 2 or CD112) and similar proteins

smart00410
Location:24 → 121

IG_like; Immunoglobulin like

pfam13927
Location:240 → 294

Ig_3; Immunoglobulin domain