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    IGD1 Igd1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850572, updated on 17-May-2024

    Summary

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    Gene symbol
    IGD1
    Gene description
    Igd1p
    Primary source
    FungiDB:YFR017C
    Locus tag
    YFR017C
    See related
    SGD:S000001913; AllianceGenome:SGD:S000001913; VEuPathDB:YFR017C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables enzyme inhibitor activity. Involved in negative regulation of glycogen catabolic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See IGD1 in Genome Data Viewer
    Location:
    chromosome: VI
    Exon count:
    1
    Sequence:
    Chromosome: VI; NC_001138.5 (182274..182861, complement)

    Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene Aip5p Neighboring gene tRNA-Gly Neighboring gene uncharacterized protein Neighboring gene 1-phosphatidylinositol-3-phosphate 5-kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001138.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Saccharomyces cerevisiae fermentation stress response protein Igd1p/Yfr017p regulates glycogen levels by inhibiting the glycogen debranching enzyme. Walkey CJ, et al. FEMS Yeast Res, 2011 Sep. PMID 21585652
    2. Mutations of the TATA-binding protein confer enhanced tolerance to hyperosmotic stress in Saccharomyces cerevisiae. Kim NR, et al. Appl Microbiol Biotechnol, 2013 Sep. PMID 23709042
    3. Construction of Saccharomyces cerevisiae strains with enhanced ethanol tolerance by mutagenesis of the TATA-binding protein gene and identification of novel genes associated with ethanol tolerance. Yang J, et al. Biotechnol Bioeng, 2011 Aug. PMID 21437883
    4. Combining chemical genetics and proteomics to identify protein kinase substrates. Dephoure N, et al. Proc Natl Acad Sci U S A, 2005 Dec 13. PMID 16330754, Free PMC Article
    5. Global protein expression profiling of budding yeast in response to DNA damage. Lee MW, et al. Yeast, 2007 Mar. PMID 17351896

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables enzyme inhibitor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables enzyme inhibitor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycogen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of glycogen catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Igd1p
    NP_116672.1
    • Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity; required for normal intracellular accumulation of glycogen; phosphorylated in vivo; expression increases during wine fermentation; protein abundance increases in response to DNA replication stress; IGD1 has a paralog, YOL024W, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001138.5 Reference assembly

      Range
      182274..182861 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179982.1 → NP_116672.1  TPA: Igd1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_116672.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTP8, P43598
      UniProtKB/TrEMBL
      A0A8H8ULA0, A7A255, B3LUM6, C7GYC3, C8Z7V2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43598.1

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