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    yciH putative translation factor [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947058, updated on 4-Apr-2024

    Summary

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    Gene symbol
    yciH
    Gene description
    putative translation factor
    Primary source
    ASAP:ABE-0004307
    Locus tag
    b1282
    See related
    ECOCYC:EG11128
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1277
    Summary
    YciH binds 30S weakly and does not promote disassociation of subunits. [More information is available at EcoGene: EG11128]. YciH has similarity to eIF1, a eukaryotic translation initiation factor which is functionally equivalent to the eubacterial IF3, with the exception of the proofreading function of the IF3 C-terminal domain . [More information is available at EcoCyc: EG11128].
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    Genomic context

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    Sequence:
    NC_000913.3 (1342658..1342984)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipopolysaccharide assembly protein A Neighboring gene lipopolysaccharide assembly protein B Neighboring gene orotidine-5'-phosphate decarboxylase Neighboring gene osmotically-inducible lipoprotein OsmB Neighboring gene DNA-binding transcriptional dual regulator YciT

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH. Lomakin IB, et al. EMBO J, 2006 Jan 11. PMID 16362046, Free PMC Article
    2. Nucleotide sequence and characterization of the pyrF operon of Escherichia coli K12. Turnbough CL Jr, et al. J Biol Chem, 1987 Jul 25. PMID 2956254
    3. Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress. Nonaka G, et al. Genes Dev, 2006 Jul 1. PMID 16818608, Free PMC Article
    4. A phylogenetic approach to target selection for structural genomics: solution structure of YciH. Cort JR, et al. Nucleic Acids Res, 1999 Oct 15. PMID 10497266, Free PMC Article
    5. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribosomal small subunit binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in formation of translation preinitiation complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translation reinitiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translational initiation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative translation factor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1342658..1342984
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415798.2 putative translation factor [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415798.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3I9U9, A0A1X3J1K0, A0A1X3JIV9, E1IJX0, E1J7U6, E6BMY7, F4V1E9, F4VBW4, J7QE02
      Conserved Domains (1) summary
      PRK09019
      Location:1 → 108
      PRK09019; stress response translation initiation inhibitor YciH
    Nucleotide Protein
    Heading Accession and Version

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