Armt1 acidic residue methyltransferase 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Armt1provided by RGD
Official Full Name: acidic residue methyltransferase 1provided by RGD
Primary source: RGD:1305235
See related: Ensembl:ENSRNOG00000019489 AllianceGenome:RGD:1305235
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1305235
Summary: Predicted to enable enzyme binding activity; methyltransferase activity; and phosphatase activity. Predicted to be involved in methylation and regulation of response to DNA damage stimulus. Orthologous to human ARMT1 (acidic residue methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 129.7), Testes (RPKM 100.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q11

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (43299916..43323675)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (40894558..40918302)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (40982761..41006371)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables S-adenosylmethionine-dependent methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables S-adenosylmethionine-dependent methyltransferase activity	ISO Inferred from Sequence Orthology more info
enables S-adenosylmethionine-dependent methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables enzyme binding	IEA Inferred from Electronic Annotation more info
enables enzyme binding	ISO Inferred from Sequence Orthology more info
enables fructose 6-phosphate aldolase activity	IEA Inferred from Electronic Annotation more info
enables fructose-1-phosphatase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein carboxyl O-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein carboxyl O-methyltransferase activity	ISO Inferred from Sequence Orthology more info
enables protein carboxyl O-methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein-glutamate O-methyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA damage response	IBA Inferred from Biological aspect of Ancestor more info
involved_in DNA damage response	IEA Inferred from Electronic Annotation more info
involved_in DNA damage response	ISO Inferred from Sequence Orthology more info
involved_in DNA damage response	ISS Inferred from Sequence or Structural Similarity more info
involved_in methylation	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: damage-control phosphatase ARMT1

Names: UPF0364 protein C6orf211 homolog; protein-glutamate O-methyltransferase; sugar phosphate phosphatase ARMT1

NP_001017447.1

EC 2.1.1.-

EC 3.1.3.-

XP_006227895.1

EC 2.1.1.-

EC 3.1.3.-

XP_017444359.1

EC 2.1.1.-

EC 3.1.3.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017447.1 → NP_001017447.1 damage-control phosphatase ARMT1

See identical proteins and their annotated locations for NP_001017447.1

Status: PROVISIONAL

Source sequence(s)

BC078920

UniProtKB/Swiss-Prot

Q6AYT5

UniProtKB/TrEMBL

A0A8I6A1F9, A6KIL4

Related

ENSRNOP00000026367.4, ENSRNOT00000026367.7

Conserved Domains (1) summary

pfam01937
Location:20 → 417

DUF89; Protein of unknown function DUF89

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

43299916..43323675

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017588870.2 → XP_017444359.1 damage-control phosphatase ARMT1 isoform X2

UniProtKB/TrEMBL

A6KIL7
XM_006227833.5 → XP_006227895.1 damage-control phosphatase ARMT1 isoform X1

UniProtKB/TrEMBL

A6KIL7

Conserved Domains (1) summary

pfam01937
Location:78 → 359

DUF89; Protein of unknown function DUF89