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    CCDC86 coiled-coil domain containing 86 [ Homo sapiens (human) ]

    Gene ID: 79080, updated on 8-Aug-2021

    Summary

    Official Symbol
    CCDC86provided by HGNC
    Official Full Name
    coiled-coil domain containing 86provided by HGNC
    Primary source
    HGNC:HGNC:28359
    See related
    Ensembl:ENSG00000110104 MIM:611293
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in testis (RPKM 26.3), adrenal (RPKM 10.0) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See CCDC86 in Genome Data Viewer
    Location:
    11q12.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (60842113..60851081)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (60609586..60618554)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene membrane spanning 4-domains A15 Neighboring gene uncharacterized LOC105369322 Neighboring gene membrane spanning 4-domains A10 Neighboring gene prostaglandin D2 receptor 2 Neighboring gene zona pellucida glycoprotein 1 Neighboring gene pre-mRNA processing factor 19

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.
    GeneReviews: Not available

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC2574, FLJ22321

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome IDA
    Inferred from Direct Assay
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 86
    Names
    cyclon
    cytokine-induced protein with coiled-coil domain

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024098.4NP_077003.1  coiled-coil domain-containing protein 86

      See identical proteins and their annotated locations for NP_077003.1

      Status: VALIDATED

      Source sequence(s)
      AP000777
      Consensus CDS
      CCDS7993.1
      UniProtKB/Swiss-Prot
      Q9H6F5
      Related
      ENSP00000227520.5, ENST00000227520.10
      Conserved Domains (2) summary
      pfam03879
      Location:236338
      Cgr1; Cgr1 family
      pfam05934
      Location:56201
      MCLC; Mid-1-related chloride channel (MCLC)

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

      Range
      60842113..60851081
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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