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    ATG4A autophagy related 4A cysteine peptidase [ Gallus gallus (chicken) ]

    Gene ID: 772074, updated on 6-Jun-2024

    Summary

    Symbol
    ATG4Aprovided by CGNC
    Full Name
    autophagy related 4A cysteine peptidaseprovided by CGNC
    Primary source
    CGNC:6275
    See related
    Ensembl:ENSGALG00010015782
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    APG4A
    Orthologs
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    Genomic context

    See ATG4A in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (14061126..14072849, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (14093489..14105204, complement)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene insulin receptor substrate 4 Neighboring gene collagen type IV alpha 5 chain Neighboring gene collagen type IV alpha 6 chain Neighboring gene proteasome 26S subunit, non-ATPase 10 Neighboring gene V-set and immunoglobulin domain containing 1

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    cysteine protease ATG4A
    Names
    ATG4 autophagy related 4 homolog A
    autophagy-related protein 4 homolog A
    NP_001258915.1
    NP_001258916.1
    NP_001384444.1
    NP_001384445.1
    NP_001384446.1
    XP_040555057.1
    XP_046772565.1
    XP_046772566.1
    XP_046796312.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271986.2NP_001258915.1  cysteine protease ATG4A isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      JAENSK010000071
      UniProtKB/TrEMBL
      A0A1I7Q405, A0A8V0YLU0
      Related
      ENSGALP00010021926.1, ENSGALT00010038003.1
      Conserved Domains (1) summary
      pfam03416
      Location:43335
      Peptidase_C54; Peptidase family C54
    2. NM_001271987.2NP_001258916.1  cysteine protease ATG4A isoform 2

      See identical proteins and their annotated locations for NP_001258916.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      JAENSK010000071
      UniProtKB/Swiss-Prot
      Q5ZIW7
      UniProtKB/TrEMBL
      A0A8V0YZZ2
      Related
      ENSGALP00010021923.1, ENSGALT00010037999.1
      Conserved Domains (1) summary
      pfam03416
      Location:26318
      Peptidase_C54; Peptidase family C54
    3. NM_001397515.1NP_001384444.1  cysteine protease ATG4A isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000071
      UniProtKB/TrEMBL
      A0A8V0YLU0
      Conserved Domains (1) summary
      pfam03416
      Location:42301
      Peptidase_C54; Peptidase family C54
    4. NM_001397516.1NP_001384445.1  cysteine protease ATG4A isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000071
      UniProtKB/TrEMBL
      A0A8V0YV28
      Related
      ENSGALP00010021920.1, ENSGALT00010037995.1
    5. NM_001397517.1NP_001384446.1  cysteine protease ATG4A isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000071
      UniProtKB/TrEMBL
      A0A8V0YZZ2

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      14061126..14072849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040699123.2XP_040555057.1  cysteine protease ATG4A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YZZ2
    2. XM_046940356.1XP_046796312.1  cysteine protease ATG4A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YZZ2

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      14093489..14105204 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046916609.1XP_046772565.1  cysteine protease ATG4A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YZZ2
    2. XM_046916610.1XP_046772566.1  cysteine protease ATG4A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YZZ2