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    PDE4D phosphodiesterase 4D [ Gallus gallus (chicken) ]

    Gene ID: 769469, updated on 3-Apr-2024

    Summary

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    Symbol
    PDE4Dprovided by CGNC
    Full Name
    phosphodiesterase 4Dprovided by CGNC
    Primary source
    CGNC:55275
    See related
    Ensembl:ENSGALG00010015196
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PDE4D in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (18792229..19379143, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (18792229..19379143, complement)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene polo like kinase 2 Neighboring gene RAB3C, member RAS oncogene family Neighboring gene uncharacterized LOC112530772 Neighboring gene uncharacterized LOC121108599 Neighboring gene DEP domain containing 1B Neighboring gene microRNA 1584

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane transporter binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cAMP catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cAMP-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cardiac muscle cell contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cAMP-specific 3',5'-cyclic phosphodiesterase 4D
    Names
    phosphodiesterase 4D, cAMP-specific
    XP_004937309.1
    XP_004937313.1
    XP_004937314.1
    XP_004937315.1
    XP_004937316.1
    XP_015133075.1
    XP_015133076.3
    XP_025001019.1
    XP_025001021.1
    XP_040512409.1
    XP_040512410.1
    XP_040512413.1
    XP_046761473.1
    XP_046761474.1
    XP_046761475.1
    XP_046791534.1
    XP_046791535.1
    XP_046791536.1
    XP_046791537.1
    XP_046791539.1
    XP_046791540.1
    XP_046791541.1
    XP_046791542.1
    XP_046791543.1
    XP_046791544.1
    XP_046791545.1
    XP_046791546.1
    XP_046791547.1
    XP_046791548.1
    XP_046791549.1
    XP_046791550.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      18792229..19379143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040656476.2 → XP_040512410.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2

      UniProtKB/TrEMBL
      A0A8V0YRP3
      Conserved Domains (2) summary
      pfam00233
      Location:402 → 643
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam18100
      Location:164 → 280
      PDE4_UCR; Phosphodiesterase 4 upstream conserved regions (UCR)

    2. XM_040656475.2 → XP_040512409.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2

      UniProtKB/TrEMBL
      A0A8V0YRP3
      Conserved Domains (2) summary
      pfam00233
      Location:402 → 643
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam18100
      Location:164 → 280
      PDE4_UCR; Phosphodiesterase 4 upstream conserved regions (UCR)

    3. XM_004937252.5 → XP_004937309.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2

      UniProtKB/TrEMBL
      A0A8V0YRP3
      Conserved Domains (2) summary
      pfam00233
      Location:402 → 643
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam18100
      Location:164 → 280
      PDE4_UCR; Phosphodiesterase 4 upstream conserved regions (UCR)

    4. XM_015277589.4 → XP_015133075.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2

      UniProtKB/TrEMBL
      A0A8V0YRP3
      Conserved Domains (2) summary
      pfam00233
      Location:402 → 643
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
      pfam18100
      Location:164 → 280
      PDE4_UCR; Phosphodiesterase 4 upstream conserved regions (UCR)

    5. XM_015277590.4 → XP_015133076.3  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1

      UniProtKB/TrEMBL
      A0A8V0YRP3
      Conserved Domains (1) summary
      cd00077
      Location:444 → 626
      HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

    6. XM_025145253.3 → XP_025001021.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10

      UniProtKB/TrEMBL
      A0A8V0YRP3
      Conserved Domains (2) summary
      pfam17084
      Location:57 → 327
      TDA11; Topoisomerase I damage affected protein 11
      pfam00233
      Location:408 → 645
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    7. XM_025145251.3 → XP_025001019.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3

      UniProtKB/TrEMBL
      A0A8V0YRP3
      Conserved Domains (2) summary
      pfam17084
      Location:57 → 318
      TDA11; Topoisomerase I damage affected protein 11
      pfam00233
      Location:399 → 636
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    8. XM_004937258.5 → XP_004937315.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6

      UniProtKB/TrEMBL
      A0A8V0YRP3
      Conserved Domains (1) summary
      pfam00233
      Location:325 → 566
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    9. XM_004937256.5 → XP_004937313.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4

      UniProtKB/TrEMBL
      A0A1D5PP20, A0A8V0YRP3
      Related
      ENSGALP00010021366.1, ENSGALT00010036633.1
      Conserved Domains (1) summary
      pfam00233
      Location:339 → 580
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    10. XM_004937257.5 → XP_004937314.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5

      UniProtKB/TrEMBL
      A0A8V0YRP3
      Related
      ENSGALP00010021364.1, ENSGALT00010036631.1
      Conserved Domains (1) summary
      pfam00233
      Location:331 → 572
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    11. XM_046905517.1 → XP_046761473.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8

    12. XM_046905518.1 → XP_046761474.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8

      Related
      ENSGALP00010021358.1, ENSGALT00010036625.1

    13. XM_004937259.5 → XP_004937316.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7

      UniProtKB/TrEMBL
      A0A3Q2UN62, A0A8V0YTD3
      Related
      ENSGALP00010021353.1, ENSGALT00010036620.1
      Conserved Domains (1) summary
      pfam00233
      Location:170 → 411
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    14. XM_046905519.1 → XP_046761475.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9

    15. XM_040656479.2 → XP_040512413.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      18792229..19379143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046935580.1 → XP_046791536.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2

    2. XM_046935579.1 → XP_046791535.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2

    3. XM_046935581.1 → XP_046791537.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2

    4. XM_046935583.1 → XP_046791539.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2

    5. XM_046935578.1 → XP_046791534.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1

    6. XM_046935594.1 → XP_046791550.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10

    7. XM_046935584.1 → XP_046791540.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3

    8. XM_046935587.1 → XP_046791543.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6

    9. XM_046935585.1 → XP_046791541.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4

      UniProtKB/TrEMBL
      A0A1D5PP20

    10. XM_046935586.1 → XP_046791542.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5

    11. XM_046935589.1 → XP_046791545.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8

    12. XM_046935590.1 → XP_046791546.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8

    13. XM_046935588.1 → XP_046791544.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7

      UniProtKB/TrEMBL
      A0A8V0YTD3

    14. XM_046935592.1 → XP_046791548.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9

    15. XM_046935593.1 → XP_046791549.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9

    16. XM_046935591.1 → XP_046791547.1  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X11

    Nucleotide Protein Strain
    Heading Accession and Version

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