U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    DAAM2 dishevelled associated activator of morphogenesis 2 [ Gallus gallus (chicken) ]

    Gene ID: 421422, updated on 6-Jun-2024

    Summary

    Go to the top of the page Help
    Symbol
    DAAM2provided by CGNC
    Full Name
    dishevelled associated activator of morphogenesis 2provided by CGNC
    Primary source
    CGNC:7646
    See related
    Ensembl:ENSGALG00010020120
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DAAM2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (28421135..28628458, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (28345618..28552959, complement)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110312 Neighboring gene uncharacterized LOC107052916 Neighboring gene molybdenum cofactor synthesis 1 Neighboring gene kinesin family member 6 Neighboring gene potassium two pore domain channel subfamily K member 16

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord. Lee HK, et al. Dev Cell, 2012 Jan 17. PMID 22227309, Free PMC Article
    2. Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system. Kida Y, et al. Brain Res Dev Brain Res, 2004 Oct 15. PMID 15464228
    3. A set of testis-specific novel genes collected from a collection of Korean Native Chicken ESTs. Shin JH, et al. Anim Genet, 2005 Aug. PMID 16026346
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord.
      Title: Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord.
    2. involved in pivotal steps in neuronal cell differentiation and movement
      Title: Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of oligodendrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of non-canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    disheveled-associated activator of morphogenesis 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396527.1 → NP_001383456.1  disheveled-associated activator of morphogenesis 2

      Status: VALIDATED

      Source sequence(s)
      BX933940, CO770487, CV036952, JAENSK010000063
      UniProtKB/TrEMBL
      A0A8V0ZDB0, A0A8V0ZJC0
      Related
      ENSGALP00010028698.1, ENSGALT00010048607.1
      Conserved Domains (4) summary
      pfam06367
      Location:312 → 516
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:686 → 1070
      FH2; Formin Homology 2 Domain
      pfam06133
      Location:510 → 594
      Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
      pfam06371
      Location:124 → 309
      Drf_GBD; Diaphanous GTPase-binding Domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      28421135..28628458 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040697627.2 → XP_040553561.1  disheveled-associated activator of morphogenesis 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZBV3
      Related
      ENSGALP00010028694.1, ENSGALT00010048603.1
      Conserved Domains (2) summary
      smart00498
      Location:639 → 1082
      FH2; Formin Homology 2 Domain
      pfam06367
      Location:264 → 468
      Drf_FH3; Diaphanous FH3 Domain

    2. XM_040697625.2 → XP_040553559.1  disheveled-associated activator of morphogenesis 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZDB0, A0A8V0ZJC0
      Conserved Domains (4) summary
      pfam06367
      Location:312 → 516
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:686 → 1070
      FH2; Formin Homology 2 Domain
      pfam06133
      Location:510 → 594
      Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
      pfam06371
      Location:124 → 309
      Drf_GBD; Diaphanous GTPase-binding Domain

    3. XM_046938818.1 → XP_046794774.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8

    4. XM_046938816.1 → XP_046794772.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8

    5. XM_046938814.1 → XP_046794770.1  disheveled-associated activator of morphogenesis 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZBV3

    6. XM_040697626.2 → XP_040553560.1  disheveled-associated activator of morphogenesis 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZDB0, A0A8V0ZJC0
      Related
      ENSGALP00010028700.1, ENSGALT00010048609.1
      Conserved Domains (4) summary
      pfam06367
      Location:312 → 516
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:686 → 1070
      FH2; Formin Homology 2 Domain
      pfam06133
      Location:510 → 594
      Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
      pfam06371
      Location:124 → 309
      Drf_GBD; Diaphanous GTPase-binding Domain

    7. XM_046938817.1 → XP_046794773.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8

    8. XM_004935382.5 → XP_004935439.2  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8
      Conserved Domains (3) summary
      pfam06367
      Location:234 → 438
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:608 → 992
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:46 → 231
      Drf_GBD; Diaphanous GTPase-binding Domain

    9. XM_025148875.3 → XP_025004643.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8
      Related
      ENSGALP00010028691.1, ENSGALT00010048600.1
      Conserved Domains (3) summary
      pfam06367
      Location:234 → 438
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:608 → 992
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:46 → 231
      Drf_GBD; Diaphanous GTPase-binding Domain

    10. XM_004935381.5 → XP_004935438.2  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8
      Conserved Domains (3) summary
      pfam06367
      Location:234 → 438
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:608 → 992
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:46 → 231
      Drf_GBD; Diaphanous GTPase-binding Domain

    11. XM_025148874.3 → XP_025004642.2  disheveled-associated activator of morphogenesis 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZDB0

    12. XM_046938813.1 → XP_046794769.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZDB0

    13. XM_046938815.1 → XP_046794771.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8

    14. XM_015283804.4 → XP_015139290.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8
      Conserved Domains (3) summary
      pfam06367
      Location:234 → 438
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:608 → 992
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:46 → 231
      Drf_GBD; Diaphanous GTPase-binding Domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      28345618..28552959 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040667571.2 → XP_040523505.1  disheveled-associated activator of morphogenesis 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZBV3
      Conserved Domains (2) summary
      smart00498
      Location:639 → 1082
      FH2; Formin Homology 2 Domain
      pfam06367
      Location:264 → 468
      Drf_FH3; Diaphanous FH3 Domain

    2. XM_040667569.2 → XP_040523503.1  disheveled-associated activator of morphogenesis 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZDB0, A0A8V0ZJC0
      Conserved Domains (4) summary
      pfam06367
      Location:312 → 516
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:686 → 1070
      FH2; Formin Homology 2 Domain
      pfam06133
      Location:510 → 594
      Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
      pfam06371
      Location:124 → 309
      Drf_GBD; Diaphanous GTPase-binding Domain

    3. XM_046913819.1 → XP_046769775.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8

    4. XM_046913817.1 → XP_046769773.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8

    5. XM_046913815.1 → XP_046769771.1  disheveled-associated activator of morphogenesis 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZBV3

    6. XM_040667570.2 → XP_040523504.1  disheveled-associated activator of morphogenesis 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZDB0, A0A8V0ZJC0
      Conserved Domains (4) summary
      pfam06367
      Location:312 → 516
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:686 → 1070
      FH2; Formin Homology 2 Domain
      pfam06133
      Location:510 → 594
      Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
      pfam06371
      Location:124 → 309
      Drf_GBD; Diaphanous GTPase-binding Domain

    7. XM_046913818.1 → XP_046769774.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8

    8. XM_040667574.2 → XP_040523508.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8
      Conserved Domains (3) summary
      pfam06367
      Location:234 → 438
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:608 → 992
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:46 → 231
      Drf_GBD; Diaphanous GTPase-binding Domain

    9. XM_040667578.2 → XP_040523512.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8
      Conserved Domains (3) summary
      pfam06367
      Location:234 → 438
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:608 → 992
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:46 → 231
      Drf_GBD; Diaphanous GTPase-binding Domain

    10. XM_040667573.2 → XP_040523507.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8
      Conserved Domains (3) summary
      pfam06367
      Location:234 → 438
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:608 → 992
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:46 → 231
      Drf_GBD; Diaphanous GTPase-binding Domain

    11. XM_040667567.2 → XP_040523501.2  disheveled-associated activator of morphogenesis 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZDB0

    12. XM_046913814.1 → XP_046769770.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZDB0

    13. XM_046913816.1 → XP_046769772.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8

    14. XM_040667579.2 → XP_040523513.1  disheveled-associated activator of morphogenesis 2 isoform X5

      UniProtKB/Swiss-Prot
      A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
      UniProtKB/TrEMBL
      A0A5H1ZRJ8
      Conserved Domains (3) summary
      pfam06367
      Location:234 → 438
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:608 → 992
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:46 → 231
      Drf_GBD; Diaphanous GTPase-binding Domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A1D5P556.2 GenPept UniProtKB/Swiss-Prot:A0A1D5P556

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials