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    tuf elongation factor Tu [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 888262, updated on 6-Oct-2023

    Summary

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    Gene symbol
    tuf
    Gene description
    elongation factor Tu
    Locus tag
    Rv0685
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (784821..786011)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene 30S ribosomal protein S12 Neighboring gene 30S ribosomal protein S7 Neighboring gene elongation factor G Neighboring gene membrane protein Neighboring gene NAD-dependent oxidoreductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biophysical characterization and ligand-binding properties of the elongation factor Tu from Mycobacterium tuberculosis. Yang J, et al. Acta Biochim Biophys Sin (Shanghai), 2019 Feb 1. PMID 30615070
    2. Interaction of Mycobacterium tuberculosis elongation factor Tu with GTP is regulated by phosphorylation. Sajid A, et al. J Bacteriol, 2011 Oct. PMID 21803988, Free PMC Article
    3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that elongation factor Tu (MtbEF-Tu) protein possessed intermediate binding affinities for guanosine-5'-triphosphate (GTP) and GDP.
      Title: Biophysical characterization and ligand-binding properties of the elongation factor Tu from Mycobacterium tuberculosis.
    2. Results show that the modulation of the MtbEf-Tu-GTP interaction by phosphorylation can have an impact on cellular protein synthesis and growth.
      Title: Interaction of Mycobacterium tuberculosis elongation factor Tu with GTP is regulated by phosphorylation.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    elongation factor Tu
    NP_215199.1
    • iron-regulated

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      784821..786011
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_215199.1 elongation factor Tu [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_215199.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2I7W4F1
      Conserved Domains (1) summary
      PRK00049
      Location:1 → 396
      PRK00049; elongation factor Tu; Reviewed
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WNN1.1

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