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    ribH 6,7-dimethyl-8-ribityllumazine synthase [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 886681, updated on 27-Nov-2023

    Summary

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    Gene symbol
    ribH
    Gene description
    6,7-dimethyl-8-ribityllumazine synthase
    Locus tag
    Rv1416
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (1591671..1592153)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene riboflavin synthase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene bifunctional riboflavin biosynthesis GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase Neighboring gene membrane protein Neighboring gene lipoprotein LprH Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors. Morgunova E, et al. Biochemistry, 2005 Mar 1. PMID 15723519
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. structure is a pentamer consisting of five subunits related by 5-fold local symmetry
      Title: Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    General protein information

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    Preferred Names
    6,7-dimethyl-8-ribityllumazine synthase
    NP_215932.2
    • RibH (6,7-dimethyl-8-ribityllumazine synthase) (DMRL synthase) (lumazine synthase)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      1591671..1592153
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_215932.2 6,7-dimethyl-8-ribityllumazine synthase [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_215932.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0H3M4R6, A0A679LDN9, A0A9P2H7N2, A5U2B8, R4MG60
      Conserved Domains (1) summary
      PRK00061
      Location:13 → 139
      ribH; 6,7-dimethyl-8-ribityllumazine synthase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WHE9.1

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