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    Sfta2 surfactant associated 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 415052, updated on 19-May-2024

    Summary

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    Official Symbol
    Sfta2provided by RGD
    Official Full Name
    surfactant associated 2provided by RGD
    Primary source
    RGD:1303180
    See related
    Ensembl:ENSRNOG00000048987 AllianceGenome:RGD:1303180
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    E030032D13Rik
    Summary
    Orthologous to human SFTA2 (surfactant associated 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 140.9) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sfta2 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (3098313..3099038, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (3093569..3094299, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3604918..3605643, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483850 Neighboring gene general transcription factor 2H subunit 4 Neighboring gene valyl-tRNA synthetase 2, mitochondrial Neighboring gene mucin like 3 Neighboring gene CB741658 gene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Localization, Occurrence, and CSF Changes of SP-G, a New Surface Active Protein with Assumable Immunoregulatory Functions in the CNS. Krause M, et al. Mol Neurobiol, 2019 Apr. PMID 30032421
    2. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, et al. Genome Res, 2004 Apr. PMID 15060004, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SP-G is a potential new cerebrospinal fluid (CSF) biomarker, possibly not only reflecting aspects of CNS innate immune responses, but also rheo-dynamically relevant changes of CSF composition.
      Title: Localization, Occurrence, and CSF Changes of SP-G, a New Surface Active Protein with Assumable Immunoregulatory Functions in the CNS.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    surfactant-associated protein 2
    Names
    surfactant associated protein G

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166020.1 → NP_001159492.1  surfactant-associated protein 2 precursor

      See identical proteins and their annotated locations for NP_001159492.1

      Status: VALIDATED

      Source sequence(s)
      BX883047
      UniProtKB/TrEMBL
      A6KTA6
      Related
      ENSRNOP00000066911.2, ENSRNOT00000074460.3
      Conserved Domains (1) summary
      pfam15210
      Location:19 → 78
      SFTA2; Surfactant-associated protein 2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      3098313..3099038 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NR_002149.1: Suppressed sequence

      Description
      NR_002149.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.