U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Dipk1a divergent protein kinase domain 1A [ Mus musculus (house mouse) ]

    Gene ID: 67266, updated on 8-May-2024

    Summary

    Official Symbol
    Dipk1aprovided by MGI
    Official Full Name
    divergent protein kinase domain 1Aprovided by MGI
    Primary source
    MGI:MGI:1914516
    See related
    Ensembl:ENSMUSG00000029270 AllianceGenome:MGI:1914516
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam69a; 2900024C23Rik
    Summary
    Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Orthologous to human DIPK1A (divergent protein kinase domain 1A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 13.4), CNS E14 (RPKM 9.4) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Dipk1a in Genome Data Viewer
    Location:
    5 F; 5 52.23 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (108055908..108134943, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (107908042..107987077, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 22270 Neighboring gene ribosomal protein L5 Neighboring gene predicted gene, 26387 Neighboring gene STARR-positive B cell enhancer ABC_E4774 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:108355724-108355877 Neighboring gene STARR-positive B cell enhancer ABC_E8068 Neighboring gene STARR-positive B cell enhancer ABC_E10338 Neighboring gene STARR-positive B cell enhancer mm9_chr5:108408844-108409144 Neighboring gene STARR-positive B cell enhancer ABC_E6359 Neighboring gene predicted gene, 42150 Neighboring gene STARR-seq mESC enhancer starr_13899 Neighboring gene ribosomal protein S19, pseudogene 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC144843

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    divergent protein kinase domain 1A
    Names
    family with sequence similarity 69, member A
    protein FAM69A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026062.4NP_080338.1  divergent protein kinase domain 1A

      See identical proteins and their annotated locations for NP_080338.1

      Status: VALIDATED

      Source sequence(s)
      AK048979, AK053273, BY131147, DT926079
      Consensus CDS
      CCDS39200.1
      UniProtKB/Swiss-Prot
      Q3U5P1, Q3V308, Q9D6I7
      Related
      ENSMUSP00000031198.5, ENSMUST00000031198.11
      Conserved Domains (2) summary
      pfam12260
      Location:194396
      PIP49_C; Protein-kinase domain of FAM69
      pfam14875
      Location:20176
      PIP49_N; N-term cysteine-rich ER, FAM69

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      108055908..108134943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)