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    CG31875 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318996, updated on 10-May-2024

    Summary

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    Official Symbol
    CG31875provided by FlyBase
    Primary source
    FLYBASE:FBgn0051875
    Locus tag
    Dmel_CG31875
    See related
    AllianceGenome:FB:FBgn0051875
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT29184; CG5831; Desr; Dmel\CG31875; FBgn0051875
    Summary
    Predicted to enable transcription corepressor activity. Predicted to be involved in histone deacetylation; negative regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Predicted to be part of histone deacetylase complex and transcription regulator complex. Is expressed in central brain primordium; embryonic brain; larval ventral nerve cord; organism; and ventral nerve cord primordium. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG31875 in Genome Data Viewer
    Location:
    30F5-30F5; 2-38 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9995561..10002736, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9995561..10002736, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L13 Neighboring gene long non-coding RNA:CR13130 Neighboring gene big brain Neighboring gene Sister of Yb Neighboring gene antisense RNA:CR44873 Neighboring gene Nucleosome-destabilizing factor Neighboring gene Translocation protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Confirming candidate genes for longevity by RT-qPCR using two different genetic backgrounds and selection methods. Wit J, et al. J Insect Physiol, 2013 Mar. PMID 23357090
    2. Frequent recent origination of brain genes shaped the evolution of foraging behavior in Drosophila. Chen S, et al. Cell Rep, 2012 Feb 23. PMID 22832161, Free PMC Article
    3. FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal. Berger C, et al. Cell Rep, 2012 Aug 30. PMID 22884370, Free PMC Article
    4. Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila. Ding K, et al. G3 (Bethesda), 2022 Dec 1. PMID 36200850, Free PMC Article
    5. Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila. Bischof J, et al. Elife, 2018 Sep 24. PMID 30247122, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of histone deacetylase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31875-PA
    CG31875-PB
    CG31875-PC
    CG31875-PD
    drosophila Elm2-Sant retrogene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9995561..10002736 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001201836.2 → NP_001188765.1  uncharacterized protein Dmel_CG31875, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188765.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPD6, Q8T8U8
      Conserved Domains (1) summary
      pfam01448
      Location:18 → 63
      ELM2; ELM2 domain

    2. NM_001259029.2 → NP_001245958.1  uncharacterized protein Dmel_CG31875, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245958.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPD6, Q8T8U8
      Conserved Domains (1) summary
      pfam01448
      Location:18 → 63
      ELM2; ELM2 domain

    3. NM_001201837.2 → NP_001188766.1  uncharacterized protein Dmel_CG31875, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188766.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPD6, Q8T8U8
      Conserved Domains (1) summary
      pfam01448
      Location:18 → 63
      ELM2; ELM2 domain

    4. NM_164884.1 → NP_723509.1  uncharacterized protein Dmel_CG31875, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723509.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPD6, Q8T8U8
      Related
      FBpp0079563, FBtr0079973
      Conserved Domains (1) summary
      pfam01448
      Location:18 → 63
      ELM2; ELM2 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IPD6 Q8IPD6
    Q8T8U8 Q8T8U8

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