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    CG5111 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43085, updated on 10-May-2024

    Summary

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    Official Symbol
    CG5111provided by FlyBase
    Primary source
    FLYBASE:FBgn0039343
    Locus tag
    Dmel_CG5111
    See related
    AllianceGenome:FB:FBgn0039343
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5111
    Summary
    Predicted to be involved in protein ubiquitination and regulation of ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Orthologous to human NUB1 (negative regulator of ubiquitin like proteins 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG5111 in Genome Data Viewer
    Location:
    96E2-96E2; 3-88 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25506275..25508279)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21331997..21334001)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45651 Neighboring gene uncharacterized protein Neighboring gene musashi Neighboring gene long non-coding RNA:CR46100 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High throughput in vivo functional validation of candidate congenital heart disease genes in Drosophila. Zhu JY, et al. Elife, 2017 Jan 20. PMID 28084990, Free PMC Article
    2. How do Wolbachia modify the Drosophila ovary? New evidences support the "titration-restitution" model for the mechanisms of Wolbachia-induced CI. He Z, et al. BMC Genomics, 2019 Jul 24. PMID 31340757, Free PMC Article
    3. Integrative analysis unveils new functions for the Drosophila Cutoff protein in noncoding RNA biogenesis and gene regulation. Pritykin Y, et al. RNA, 2017 Jul. PMID 28420675, Free PMC Article
    4. The genetic basis for variation in resistance to infection in the Drosophila melanogaster genetic reference panel. Wang JB, et al. PLoS Pathog, 2017 Mar. PMID 28257468, Free PMC Article
    5. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5111-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25506275..25508279
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143145.1 → NP_651402.1  uncharacterized protein Dmel_CG5111 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651402.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MSP2, Q9VBQ3
      Related
      FBpp0084254, FBtr0084880
      Conserved Domains (3) summary
      cd14291
      Location:353 → 388
      UBA1_NUB1_like; UBA1 domain found in NEDD8 ultimate buster 1 (NUB1) and similar proteins
      cd14387
      Location:424 → 458
      UBA2_UBP13; UBA2 domain found in ubiquitin carboxyl-terminal hydrolase 13 (UBP13)
      pfam00627
      Location:475 → 511
      UBA; UBA/TS-N domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MSP2 Q8MSP2
    Q9VBQ3 Q9VBQ3

    Gene LinkOut

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