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    CG5404 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41901, updated on 10-May-2024

    Summary

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    Official Symbol
    CG5404provided by FlyBase
    Primary source
    FLYBASE:FBgn0038354
    Locus tag
    Dmel_CG5404
    See related
    AllianceGenome:FB:FBgn0038354
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5404
    Summary
    Predicted to enable anion:anion antiporter activity and sulfate transmembrane transporter activity. Predicted to be involved in sulfate transport and transmembrane transport. Predicted to be integral component of plasma membrane. Is expressed in adult head. Orthologous to human SLC26A11 (solute carrier family 26 member 11). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG5404 in Genome Data Viewer
    Location:
    89A2-89A2; 3-58 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15704676..15708434)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11530398..11534156)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45635 Neighboring gene long non-coding RNA:CR45636 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Drosophila genetic model of nephrolithiasis: transcriptional changes in response to diet induced stone formation. Chung VY, et al. BMC Urol, 2017 Nov 28. PMID 29183349, Free PMC Article
    2. Ion and solute transport by Prestin in Drosophila and Anopheles. Hirata T, et al. J Insect Physiol, 2012 Apr. PMID 22321763, Free PMC Article
    3. Copper homeostasis gene discovery in Drosophila melanogaster. Norgate M, et al. Biometals, 2007 Jun. PMID 17216353
    4. A gene-specific T2A-GAL4 library for Drosophila. Lee PT, et al. Elife, 2018 Mar 22. PMID 29565247, Free PMC Article
    5. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables sulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5404-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15704676..15708434
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142225.3 → NP_650482.1  uncharacterized protein Dmel_CG5404 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650482.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95SI2, Q9VF45
      Related
      FBpp0082619
      Conserved Domains (2) summary
      cd07042
      Location:498 → 554
      STAS_SulP_like_sulfate_transporter; Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function
      TIGR00815
      Location:50 → 557
      sulP; high affinity sulphate transporter 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VF45 Q9VF45

    Gene LinkOut

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