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    Dgcr6 DiGeorge syndrome critical region gene 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303794, updated on 29-Feb-2024

    Summary

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    Official Symbol
    Dgcr6provided by RGD
    Official Full Name
    DiGeorge syndrome critical region gene 6provided by RGD
    Primary source
    RGD:1309390
    See related
    Ensembl:ENSRNOG00000001880 AllianceGenome:RGD:1309390
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to several human genes including DGCR6L (DiGeorge syndrome critical region gene 6 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 185.0), Heart (RPKM 109.8) and 9 other tissues See more
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    Genomic context

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    See Dgcr6 in Genome Data Viewer
    Location:
    11q23
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (96432024..96442766, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (82927725..82932823, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (87076205..87081306, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene reticulon 4 receptor Neighboring gene proline dehydrogenase Neighboring gene V-set pre-B cell surrogate light chain 1B Neighboring gene uncharacterized LOC102555762

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    protein DGCR6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107080.2 → NP_001100550.1  protein DGCR6

      See identical proteins and their annotated locations for NP_001100550.1

      Status: PROVISIONAL

      Source sequence(s)
      BC158828
      UniProtKB/TrEMBL
      A6JSJ1, B0BNH6
      Conserved Domains (1) summary
      pfam07324
      Location:9 → 195
      DGCR6; DiGeorge syndrome critical region 6 (DGCR6) protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      96432024..96442766 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006248609.5 → XP_006248671.1  protein DGCR6 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AQQ6, F7FP83
      Related
      ENSRNOP00000002574.5
      Conserved Domains (1) summary
      pfam07324
      Location:9 → 198
      DGCR6; DiGeorge syndrome critical region 6 (DGCR6) protein

    2. XM_063270459.1 → XP_063126529.1  protein DGCR6 isoform X2

    3. XM_063270460.1 → XP_063126530.1  protein DGCR6 isoform X3

    4. XM_063270461.1 → XP_063126531.1  protein DGCR6 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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