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    CG3009 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31402, updated on 10-May-2024

    Summary

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    Official Symbol
    CG3009provided by FlyBase
    Primary source
    FLYBASE:FBgn0029720
    Locus tag
    Dmel_CG3009
    See related
    AllianceGenome:FB:FBgn0029720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3009
    Summary
    Predicted to enable calcium-dependent phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion and phospholipid metabolic process. Is expressed in adult head. Orthologous to human PLA2G3 (phospholipase A2 group III). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG3009 in Genome Data Viewer
    Location:
    4C11-4C11; 1-8 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (4658158..4666700, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (4552191..4560733, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L30 Neighboring gene torsin Neighboring gene cap binding protein 80 Neighboring gene uncharacterized protein Neighboring gene fizzy-related Neighboring gene Protein phosphatase 2C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Completion of mitosis requires neither fzr/rap nor fzr2, a male germline-specific Drosophila Cdh1 homolog. Jacobs H, et al. Curr Biol, 2002 Aug 20. PMID 12194827
    2. Drosophila spermatid individualization is sensitive to temperature and fatty acid metabolism. Ben-David G, et al. Spermatogenesis, 2015 Jan-Apr. PMID 26413411, Free PMC Article
    3. Multiple mechanisms drive genomic adaptation to extreme O(2) levels in Drosophila melanogaster. Iranmehr A, et al. Nat Commun, 2021 Feb 12. PMID 33579965, Free PMC Article
    4. Chemical screen reveals small molecules suppressing fragile X premutation rCGG repeat-mediated neurodegeneration in Drosophila. Qurashi A, et al. Hum Mol Genet, 2012 May 1. PMID 22298836, Free PMC Article
    5. Metabolism of sphingosine 1-phosphate and lysophosphatidic acid: a genome wide analysis of gene expression in Drosophila. Renault AD, et al. Mech Dev, 2002 Dec. PMID 14516700

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium-dependent phospholipase A2 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in arachidonic acid secretion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phospholipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3009-PA
    CG3009-PB
    CG3009-PD
    NP_001162665.1
    NP_001162666.2
    NP_572180.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      4658158..4666700 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169195.2 → NP_001162666.2  uncharacterized protein Dmel_CG3009, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162666.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJG5
      Conserved Domains (1) summary
      cd04704
      Location:102 → 198
      PLA2_bee_venom_like; PLA2_bee_venom_like: A sub-family of Phospholipase A2, similar to bee venom PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the ...

    2. NM_131952.3 → NP_572180.1  uncharacterized protein Dmel_CG3009, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572180.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXC6, Q9W4I0
      Related
      FBpp0070656
      Conserved Domains (1) summary
      cd04704
      Location:102 → 198
      PLA2_bee_venom_like; PLA2_bee_venom_like: A sub-family of Phospholipase A2, similar to bee venom PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the ...

    3. NM_001169194.2 → NP_001162665.1  uncharacterized protein Dmel_CG3009, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162665.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXC6, Q9W4I0
      Conserved Domains (1) summary
      cd04704
      Location:102 → 198
      PLA2_bee_venom_like; PLA2_bee_venom_like: A sub-family of Phospholipase A2, similar to bee venom PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JJG5 E1JJG5
    Q8SXC6 Q8SXC6
    Q9W4I0 Q9W4I0

    Gene LinkOut

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