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    Sfxn1 sideroflexin 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364678, updated on 5-Jun-2021

    Summary

    Official Symbol
    Sfxn1provided by RGD
    Official Full Name
    sideroflexin 1provided by RGD
    Primary source
    RGD:1308482
    See related
    Ensembl:ENSRNOG00000018279
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    SLC64A1
    Expression
    Biased expression in Kidney (RPKM 466.1), Liver (RPKM 145.1) and 7 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sfxn1 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (10486250..10522640, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (11046588..11082219, complement)

    Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P0-like Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene U2 spliceosomal RNA Neighboring gene dopamine receptor D1 Neighboring gene U4 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables D-serine transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables D-serine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables D-serine transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables L-serine transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables L-serine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables L-serine transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables serine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in D-serine transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in D-serine transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in D-serine transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in L-serine transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in L-serine transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-serine transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in erythrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within erythrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in iron ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within iron ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in one-carbon metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of one-carbon metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of one-carbon metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in serine import into mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in serine import into mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in serine import into mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in serine import into mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in integral component of mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sideroflexin-1
    Names
    TCC
    solute carrier family 64 member 1
    tricarboxylate carrier protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012213.1NP_001012213.1  sideroflexin-1

      See identical proteins and their annotated locations for NP_001012213.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078935
      UniProtKB/TrEMBL
      Q6AYS2
      Related
      ENSRNOP00000024707.4, ENSRNOT00000024707.7
      Conserved Domains (1) summary
      pfam03820
      Location:16322
      Mtc; Tricarboxylate carrier

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mRatBN7.2 Primary Assembly

    Genomic

    1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

      Range
      10486250..10522640 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039095969.1XP_038951897.1  sideroflexin-1 isoform X2

      Conserved Domains (1) summary
      pfam03820
      Location:10244
      Mtc; Tricarboxylate carrier
    2. XM_008771502.3XP_008769724.1  sideroflexin-1 isoform X1

      See identical proteins and their annotated locations for XP_008769724.1

      UniProtKB/TrEMBL
      Q6AYS2
      Conserved Domains (1) summary
      pfam03820
      Location:16322
      Mtc; Tricarboxylate carrier
    3. XM_039095968.1XP_038951896.1  sideroflexin-1 isoform X2

      Conserved Domains (1) summary
      pfam03820
      Location:10244
      Mtc; Tricarboxylate carrier

    RNA

    1. XR_005495309.1 RNA Sequence

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