Slfn2 schlafen family member 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slfn2provided by RGD
Official Full Name: schlafen family member 2provided by RGD
Primary source: RGD:1308645
See related: Ensembl:ENSRNOG00000037113 AllianceGenome:RGD:1308645
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in negative regulation of cell population proliferation and response to bacterium. Orthologous to human SLFN12L (schlafen family member 12 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Spleen (RPKM 713.5), Thymus (RPKM 499.7) and 7 other tissues See more
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 10q26

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (68450861..68457198)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (67953322..67959659)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (70370381..70376718)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables tRNA binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in T cell mediated immunity	ISO Inferred from Sequence Orthology more info
involved_in T cell proliferation	ISO Inferred from Sequence Orthology more info
involved_in T cell proliferation involved in immune response	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of cell population proliferation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within response to bacterium	ISO Inferred from Sequence Orthology more info
involved_in tRNA stabilization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: schlafen family member 12-like

Names: schlafen 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107031.1 → NP_001100501.1 schlafen family member 12-like

See identical proteins and their annotated locations for NP_001100501.1

Status: PROVISIONAL

Source sequence(s)

CH473948

UniProtKB/TrEMBL

A0A096MJK8, A6HHF9

Conserved Domains (2) summary

pfam04326
Location:231 → 340

AlbA_2; Putative DNA-binding domain

pfam17057
Location:123 → 231

B3R; Poxviridae B3 protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086028.1 Reference GRCr8

Range

68450861..68457198

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039086039.2 → XP_038941967.1 schlafen family member 12-like isoform X1

UniProtKB/TrEMBL

A0A096MJK8, D4A2D6

Related

ENSRNOP00000052810.3

Conserved Domains (1) summary

PHA02782
Location:17 → 339

PHA02782; hypothetical protein; Provisional