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    nucb-1 NUCleoBindin homolog [ Caenorhabditis elegans ]

    Gene ID: 181230, updated on 23-Nov-2023

    Summary

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    Gene symbol
    nucb-1
    Gene description
    NUCleoBindin homolog
    Primary source
    WormBase:WBGene00009674
    Locus tag
    CELE_F44A6.1
    See related
    AllianceGenome:WB:WBGene00009674
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be active in endoplasmic reticulum-Golgi intermediate compartment. Is expressed in body wall musculature; intestinal cell; neurons; and non-striated muscle. Orthologous to human NUCB1 (nucleobindin 1) and NUCB2 (nucleobindin 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    9
    Sequence:
    Chromosome: X; NC_003284.9 (10197706..10200375)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Myelin regulatory factor homolog 2, N-terminal Neighboring gene Arrestin C-terminal-like domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Steroid hormone receptor family member cnr14 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteins interacting with Caenorhabditis elegans Galpha subunits. Cuppen E, et al. Comp Funct Genomics, 2003. PMID 18629017, Free PMC Article
    2. Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. Shen X, et al. PLoS Genet, 2005 Sep. PMID 16184190, Free PMC Article
    3. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NUCleoBindin homolog
    NP_741885.1
    • Product from WormBase gene class nucb;
      Confirmed by transcript evidence
    NP_741886.1
    • Product from WormBase gene class nucb;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      10197706..10200375
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171970.8 → NP_741886.1  NUCleoBindin homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741886.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20384, Q86RT3
      Conserved Domains (1) summary
      pfam13499
      Location:259 → 331
      EF-hand_7; EF-hand domain pair

    2. NM_171763.5 → NP_741885.1  NUCleoBindin homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741885.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86RT3, Q8MQ51
      Conserved Domains (1) summary
      pfam13499
      Location:259 → 331
      EF-hand_7; EF-hand domain pair
    Nucleotide Protein
    Heading Accession and Version

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