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    Phf7 PHD finger protein 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364510, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Phf7provided by RGD
    Official Full Name
    PHD finger protein 7provided by RGD
    Primary source
    RGD:1308638
    See related
    Ensembl:ENSRNOG00000018996 AllianceGenome:RGD:1308638
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable metal ion binding activity. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and nuclear speck. Predicted to be active in nucleus. Orthologous to human PHF7 (PHD finger protein 7). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 1989.2) and Muscle (RPKM 58.2) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Phf7 in Genome Data Viewer
    Location:
    16p16
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (6439968..6452671, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (6433535..6446314, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (7323527..7336609, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene troponin C1, slow skeletal and cardiac type Neighboring gene semaphorin 3G Neighboring gene Brca1 associated protein 1 Neighboring gene dynein, axonemal, heavy chain 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Proteomic characterization of the human sperm nucleus. de Mateo S, et al. Proteomics, 2011 Jul. PMID 21630459
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    PHD finger protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012211.1 → NP_001012211.1  PHD finger protein 7

      See identical proteins and their annotated locations for NP_001012211.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079288
      UniProtKB/Swiss-Prot
      Q6AXW4
      UniProtKB/TrEMBL
      A0A8I6AM33
      Related
      ENSRNOP00000095148.1, ENSRNOT00000102974.1
      Conserved Domains (2) summary
      cd15496
      Location:246 → 299
      PHD_PHF7_G2E3_like; PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
      cd15669
      Location:33 → 144
      ePHD_PHF7_G2E3_like; Extended PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      6439968..6452671 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275583.1 → XP_063131653.1  PHD finger protein 7 isoform X3

    2. XM_006252632.5 → XP_006252694.1  PHD finger protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AM33, A0A8L2QKI0
      Related
      ENSRNOP00000040832.4
      Conserved Domains (2) summary
      cd15496
      Location:212 → 265
      PHD_PHF7_G2E3_like; PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
      cl22851
      Location:33 → 110
      PHD_SF; PHD finger superfamily

    3. XM_017600192.3 → XP_017455681.1  PHD finger protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AM33
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AXW4.1 GenPept UniProtKB/Swiss-Prot:Q6AXW4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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