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    CG11562 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33200, updated on 10-May-2024

    Summary

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    Official Symbol
    CG11562provided by FlyBase
    Primary source
    FLYBASE:FBgn0031247
    Locus tag
    Dmel_CG11562
    See related
    AllianceGenome:FB:FBgn0031247
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE44650; Dmel\CG11562
    Summary
    Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be active in mitochondrion. Is expressed in adult head; anterior midgut primordium; embryonic/larval midgut; organism; and posterior midgut primordium. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human PET117 (PET117 cytochrome c oxidase chaperone). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    21B7-21B7; 2-0.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (292419..293222)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (292419..293222)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46262 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46263 Neighboring gene amnionless Neighboring gene U2 small nuclear riboprotein auxiliary factor 38 Neighboring gene Stress induced phosphoprotein 1 Neighboring gene Pi3K21B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors. Wang L, et al. Genes Dev, 2006 Mar 1. PMID 16481466, Free PMC Article
    2. Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila. Coelho DS, et al. Cell Rep, 2013 Nov 14. PMID 24183663, Free PMC Article
    3. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Hollien J, et al. Science, 2006 Jul 7. PMID 16825573
    4. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
    5. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11562-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      292419..293222
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134672.2 → NP_608516.1  uncharacterized protein Dmel_CG11562 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608516.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPN3
      Related
      FBpp0077789
      Conserved Domains (1) summary
      pfam15786
      Location:5 → 68
      PET117; PET assembly of cytochrome c oxidase, mitochondrial
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPN3 Q9VPN3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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