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    CG8117 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32499, updated on 10-May-2024

    Summary

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    Official Symbol
    CG8117provided by FlyBase
    Primary source
    FLYBASE:FBgn0030663
    Locus tag
    Dmel_CG8117
    See related
    AllianceGenome:FB:FBgn0030663
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    dCrsp70; Dmel\CG8117
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human TCEA1 (transcription elongation factor A1); TCEA2 (transcription elongation factor A2); and TCEA3 (transcription elongation factor A3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG8117 in Genome Data Viewer
    Location:
    13E3-13E3; 1-51 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15644222..15644991)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15538255..15539024)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44423 Neighboring gene long non-coding RNA:CR44893 Neighboring gene antisense RNA:CR43299 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation of enhancer location in divergent insects. Cande J, et al. Proc Natl Acad Sci U S A, 2009 Aug 25. PMID 19666595, Free PMC Article
    2. Shadow enhancers as a source of evolutionary novelty. Hong JW, et al. Science, 2008 Sep 5. PMID 18772429, Free PMC Article
    3. Systematic identification of functional orthologs based on protein network comparison. Bandyopadhyay S, et al. Genome Res, 2006 Mar. PMID 16510899, Free PMC Article
    4. A core transcriptional network for early mesoderm development in Drosophila melanogaster. Sandmann T, et al. Genes Dev, 2007 Feb 15. PMID 17322403, Free PMC Article
    5. Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes. Gim BS, et al. Mol Cell Biol, 2001 Aug. PMID 11438678, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8117-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15644222..15644991
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132821.2 → NP_573049.2  uncharacterized protein Dmel_CG8117 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573049.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXS6
      Related
      FBpp0073866
      Conserved Domains (2) summary
      pfam07500
      Location:3 → 109
      TFIIS_M; Transcription factor S-II (TFIIS), central domain
      cl02609
      Location:118 → 161
      Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXS6 Q9VXS6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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