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    Ccdc112 coiled-coil domain containing 112 [ Mus musculus (house mouse) ]

    Gene ID: 240261, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ccdc112provided by MGI
    Official Full Name
    coiled-coil domain containing 112provided by MGI
    Primary source
    MGI:MGI:1918800
    See related
    Ensembl:ENSMUSG00000071855 AllianceGenome:MGI:1918800
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    8430438M01Rik
    Summary
    Orthologous to human CCDC112 (coiled-coil domain containing 112). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in CNS E18 (RPKM 3.5), CNS E14 (RPKM 2.8) and 11 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    18 C; 18 24.48 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (46415218..46445016, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (46282151..46311950, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52364 Neighboring gene protein geranylgeranyltransferase type I, beta subunit Neighboring gene STARR-positive B cell enhancer ABC_E9977 Neighboring gene STARR-seq mESC enhancer starr_44498 Neighboring gene STARR-positive B cell enhancer ABC_E1955 Neighboring gene STARR-seq mESC enhancer starr_44499 Neighboring gene STARR-seq mESC enhancer starr_44500 Neighboring gene STARR-seq mESC enhancer starr_44501 Neighboring gene STARR-seq mESC enhancer starr_44503 Neighboring gene predicted gene 4107 Neighboring gene symplekin pseudogene Neighboring gene STARR-seq mESC enhancer starr_44504 Neighboring gene STARR-seq mESC enhancer starr_44505 Neighboring gene predicted gene, 57821

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Diversification of stem cell molecular repertoire by alternative splicing. Pritsker M, et al. Proc Natl Acad Sci U S A, 2005 Oct 4. PMID 16183747, Free PMC Article
    2. A molecular profile of a hematopoietic stem cell niche. Hackney JA, et al. Proc Natl Acad Sci U S A, 2002 Oct 1. PMID 12226475, Free PMC Article
    3. A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Breslow DK, et al. Nat Genet, 2018 Mar. PMID 29459677, Free PMC Article
    4. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 112

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001160399.1 → NP_001153871.1  coiled-coil domain-containing protein 112 precursor

      See identical proteins and their annotated locations for NP_001153871.1

      Status: VALIDATED

      Source sequence(s)
      AA241279, AC124717, AC148019, AW491530, BQ831910, CJ174591, DT929545, DV656314
      Consensus CDS
      CCDS50281.1
      UniProtKB/Swiss-Prot
      A0AUP1, A0AUP2
      UniProtKB/TrEMBL
      D3Z1J2
      Related
      ENSMUSP00000072614.7, ENSMUST00000072835.7
      Conserved Domains (1) summary
      PTZ00121
      Location:339 → 479
      PTZ00121; MAEBL; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      46415218..46445016 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246924.4 → XP_011245226.1  coiled-coil domain-containing protein 112 isoform X1

      Conserved Domains (1) summary
      PTZ00121
      Location:66 → 475
      PTZ00121; MAEBL; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0AUP1.2 GenPept UniProtKB/Swiss-Prot:A0AUP1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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