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    Lurap1l leucine rich adaptor protein 1-like [ Mus musculus (house mouse) ]

    Gene ID: 52829, updated on 5-Mar-2024

    Summary

    Official Symbol
    Lurap1lprovided by MGI
    Official Full Name
    leucine rich adaptor protein 1-likeprovided by MGI
    Primary source
    MGI:MGI:106510
    See related
    Ensembl:ENSMUSG00000048706 AllianceGenome:MGI:106510
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    WI-13707; D4Bwg0951e; bM350F23.1; 1110029A09Rik
    Summary
    Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. Is expressed in embryo mesenchyme; jaw; rib; and stomach. Orthologous to human LURAP1L (leucine rich adaptor protein 1 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in colon adult (RPKM 59.0), duodenum adult (RPKM 29.9) and 17 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    4 C3; 4 37.91 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (80828923..80872538)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (80910686..80954301)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10592 Neighboring gene predicted gene, 57729 Neighboring gene STARR-seq mESC enhancer starr_10593 Neighboring gene STARR-seq mESC enhancer starr_10594 Neighboring gene STARR-seq mESC enhancer starr_10595 Neighboring gene tyrosinase-related protein 1 Neighboring gene STARR-seq mESC enhancer starr_10596 Neighboring gene STARR-seq mESC enhancer starr_10597 Neighboring gene STARR-seq mESC enhancer starr_10598 Neighboring gene STARR-seq mESC enhancer starr_10599 Neighboring gene multiple PDZ domain crumbs cell polarity complex component Neighboring gene predicted gene, 25803 Neighboring gene predicted gene 11765

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    leucine rich adaptor protein 1-like
    Names
    amplimer WI-13707, mouse homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026821.5NP_081097.2  leucine rich adaptor protein 1-like

      See identical proteins and their annotated locations for NP_081097.2

      Status: PROVISIONAL

      Source sequence(s)
      AL844604
      Consensus CDS
      CCDS18291.1
      UniProtKB/Swiss-Prot
      A2AQI1, Q8K2P1, Q9D150
      Related
      ENSMUSP00000062628.4, ENSMUST00000055922.4
      Conserved Domains (1) summary
      pfam14854
      Location:76186
      LURAP; Leucine rich adaptor protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      80828923..80872538
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)