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    Banp Btg3 associated nuclear protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292064, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Banpprovided by RGD
    Official Full Name
    Btg3 associated nuclear proteinprovided by RGD
    Primary source
    RGD:1307464
    See related
    Ensembl:ENSRNOG00000019140 AllianceGenome:RGD:1307464
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable identical protein binding activity and p53 binding activity. Predicted to be involved in negative regulation of protein catabolic process; positive regulation of transcription, DNA-templated; and protein localization to nucleus. Predicted to be located in nuclear body. Orthologous to human BANP (BTG3 associated nuclear protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 55.5), Lung (RPKM 53.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Banp in Genome Data Viewer
    Location:
    19q12
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (66916417..66994286)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (50007710..50082742)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (54766441..54843795)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102550600 Neighboring gene carbonic anhydrase 5A Neighboring gene zinc finger protein 469 Neighboring gene uncharacterized LOC120098606 Neighboring gene zinc finger protein, multitype 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Regulation of GAD65 expression by SMAR1 and p53 upon Streptozotocin treatment. Singh S, et al. BMC Mol Biol, 2012 Sep 14. PMID 22978699, Free PMC Article
    2. Identification and molecular analysis of BANP. Birot A, et al. Gene, 2000 Aug 8. PMID 10940556
    3. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Yang X, et al. Cell, 2016 Feb 11. PMID 26871637, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BANP Participates in the Chronic Intermittent Hypoxia-Induced Senescence of Vascular Endothelial Cells by Promoting P53 Phosphorylation and Nuclear Retention.
      Title: BANP Participates in the Chronic Intermittent Hypoxia-Induced Senescence of Vascular Endothelial Cells by Promoting P53 Phosphorylation and Nuclear Retention.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables p53 binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within negative regulation of protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein localization to nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein localization to nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein BANP

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106191.2 → NP_001099661.1  protein BANP

      See identical proteins and their annotated locations for NP_001099661.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A0A8I6A879, A6IZQ7, B1H235
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    2. NM_001419509.1 → NP_001406438.1  protein BANP

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A0A8I6A879, A6IZQ7, B1H235
      Related
      ENSRNOP00000088499.1, ENSRNOT00000106448.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      66916417..66994286
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277948.1 → XP_063134018.1  protein BANP isoform X5

      UniProtKB/TrEMBL
      A0A8I6AGC7

    2. XM_006255752.5 → XP_006255814.1  protein BANP isoform X2

      UniProtKB/TrEMBL
      F7F0I6
      Related
      ENSRNOP00000025894.6
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    3. XM_006255756.5 → XP_006255818.1  protein BANP isoform X6

      Related
      ENSRNOP00000092851.1
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    4. XM_006255753.5 → XP_006255815.1  protein BANP isoform X3

      See identical proteins and their annotated locations for XP_006255815.1

      UniProtKB/TrEMBL
      A0A8I6A1X0, A6IZQ8
      Related
      ENSRNOP00000085557.1
      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    5. XM_006255754.5 → XP_006255816.1  protein BANP isoform X4

      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    6. XM_006255757.5 → XP_006255819.1  protein BANP isoform X7

      Conserved Domains (1) summary
      smart01025
      Location:218 → 291
      BEN; The BEN domain is found in diverse animal proteins

    7. XM_008772601.4 → XP_008770823.1  protein BANP isoform X1

      See identical proteins and their annotated locations for XP_008770823.1

      UniProtKB/TrEMBL
      A0A8I6A879, A6IZQ7, B1H235
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    8. XM_063277946.1 → XP_063134016.1  protein BANP isoform X2

      UniProtKB/TrEMBL
      F7F0I6

    9. XM_063277947.1 → XP_063134017.1  protein BANP isoform X4

    10. XM_039097647.2 → XP_038953575.1  protein BANP isoform X1

      UniProtKB/TrEMBL
      A0A8I6A879, A6IZQ7, B1H235
      Conserved Domains (1) summary
      smart01025
      Location:257 → 330
      BEN; The BEN domain is found in diverse animal proteins

    11. XM_039097650.2 → XP_038953578.1  protein BANP isoform X8

      Conserved Domains (1) summary
      smart01025
      Location:116 → 189
      BEN; The BEN domain is found in diverse animal proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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