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    Sdf2 stromal cell derived factor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287470, updated on 5-Mar-2024

    Summary

    Official Symbol
    Sdf2provided by RGD
    Official Full Name
    stromal cell derived factor 2provided by RGD
    Primary source
    RGD:1307274
    See related
    Ensembl:ENSRNOG00000012121 AllianceGenome:RGD:1307274
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable misfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to be located in endoplasmic reticulum. Predicted to be part of chaperone complex. Orthologous to human SDF2 (stromal cell derived factor 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 274.7), Kidney (RPKM 216.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Sdf2 in Genome Data Viewer
    Location:
    10q25
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (63638634..63649109)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (63140563..63151038)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (65507364..65517839)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene RAB34, member RAS oncogene family Neighboring gene protein interacting with cyclin A1 Neighboring gene SPT6 homolog, histone chaperone and transcription elongation factor Neighboring gene bridge-like lipid transfer protein family member 2 Neighboring gene uncharacterized LOC120095269 Neighboring gene U6 spliceosomal RNA Neighboring gene ribosomal protein L37A, pseudogene 13 Neighboring gene ribosomal protein S6 kinase related

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables misfolded protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in chaperone cofactor-dependent protein refolding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein folding chaperone complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    stromal cell-derived factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105803.2NP_001099273.2  stromal cell-derived factor 2 precursor

      See identical proteins and their annotated locations for NP_001099273.2

      Status: VALIDATED

      Source sequence(s)
      BI274683, CB326294, CO570263
      UniProtKB/TrEMBL
      A6HH24, A6HH25, D4A4H5
      Related
      ENSRNOP00000016297.5, ENSRNOT00000016297.7
      Conserved Domains (1) summary
      smart00472
      Location:91146
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      63638634..63649109
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)