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    Vps35l VPS35 endosomal protein sorting factor like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361635, updated on 3-Apr-2024

    Summary

    Official Symbol
    Vps35lprovided by RGD
    Official Full Name
    VPS35 endosomal protein sorting factor likeprovided by RGD
    Primary source
    RGD:1564485
    See related
    Ensembl:ENSRNOG00000016063 AllianceGenome:RGD:1564485
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in Golgi to plasma membrane transport and endocytic recycling. Predicted to be integral component of membrane. Predicted to be active in endosome. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome. Orthologous to human VPS35L (VPS35 endosomal protein sorting factor like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 104.9), Adrenal (RPKM 99.8) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Vps35l in Genome Data Viewer
    Location:
    1q35
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (182507576..182611021)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (173076219..173179663)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (188448517..188552268)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene glycerophosphodiester phosphodiesterase 1 Neighboring gene centriolar coiled-coil protein 110 Neighboring gene small nucleolar RNA SNORA24 Neighboring gene lysine-rich nucleolar protein 1 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene IQ motif containing K

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in Golgi to plasma membrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytic recycling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endocytic recycling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endocytic recycling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytic recycling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    VPS35 endosomal protein-sorting factor-like
    Names
    UPF0505 protein C16orf62 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017463.2NP_001017463.1  VPS35 endosomal protein-sorting factor-like isoform 2

      See identical proteins and their annotated locations for NP_001017463.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/Swiss-Prot
      Q5XI83
      UniProtKB/TrEMBL
      A0A8I6AHK5
      Related
      ENSRNOP00000043528.2, ENSRNOT00000050393.3
    2. NM_001399656.1NP_001386585.1  VPS35 endosomal protein-sorting factor-like isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      Related
      ENSRNOP00000093416.1, ENSRNOT00000105295.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      182507576..182611021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017589391.3XP_017444880.1  VPS35 endosomal protein-sorting factor-like isoform X1

      UniProtKB/TrEMBL
      A0A8I6AHK5