Spata6 spermatogenesis associated 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Spata6provided by RGD
Official Full Name: spermatogenesis associated 6provided by RGD
Primary source: RGD:628657
See related: Ensembl:ENSRNOG00000007568 AllianceGenome:RGD:628657
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Hash
Summary: Predicted to enable myosin light chain binding activity. Predicted to be involved in motile cilium assembly and spermatogenesis. Predicted to be located in extracellular region. Predicted to be active in sperm connecting piece. Orthologous to human SPATA6 (spermatogenesis associated 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 1846.8) and Lung (RPKM 72.1) See more
Orthologs: human mouse all
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Genomic context

Location:: 5q35

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (131821585..131905011)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (126593122..126676557)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (131719922..131803853)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

42.MMHAP10FF6.seq (e-PCR)
- UniSTS:124452

D5Uwm71 (e-PCR)
- UniSTS:534566

AU048201 (e-PCR)
- UniSTS:109771

Spata6 (e-PCR), detects polymorphism
- UniSTS:496621

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables myosin light chain binding	IBA Inferred from Biological aspect of Ancestor more info
enables myosin light chain binding	IEA Inferred from Electronic Annotation more info
enables myosin light chain binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in motile cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in motile cilium assembly	IEA Inferred from Electronic Annotation more info
involved_in motile cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in motile cilium assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in spermatogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in spermatogenesis	IEA Inferred from Electronic Annotation more info
involved_in spermatogenesis	ISO Inferred from Sequence Orthology more info
involved_in spermatogenesis	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in sperm connecting piece	IBA Inferred from Biological aspect of Ancestor more info
located_in sperm connecting piece	IEA Inferred from Electronic Annotation more info
located_in sperm connecting piece	ISO Inferred from Sequence Orthology more info
located_in sperm connecting piece	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: spermatogenesis-associated protein 6

Names: kinesin-related protein HASH; spermatogenesis-related factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_134392.2 → NP_599219.2 spermatogenesis-associated protein 6 precursor

See identical proteins and their annotated locations for NP_599219.2

Status: VALIDATED

Source sequence(s)

BC158581, JAXUCZ010000005

UniProtKB/Swiss-Prot

A0JN12, Q99MU5, Q9EQU0

UniProtKB/TrEMBL

A6JZ10

Related

ENSRNOP00000010524.4, ENSRNOT00000010524.5

Conserved Domains (1) summary

pfam14909
Location:11 → 149

SPATA6; Spermatogenesis-assoc protein 6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086023.1 Reference GRCr8

Range

131821585..131905011

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039109229.2 → XP_038965157.1 spermatogenesis-associated protein 6 isoform X1

UniProtKB/TrEMBL

A0A8I5ZST2

Conserved Domains (1) summary

pfam14909
Location:1 → 41

SPATA6; Spermatogenesis-assoc protein 6
XM_039109230.2 → XP_038965158.1 spermatogenesis-associated protein 6 isoform X2