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    Scrg1 stimulator of chondrogenesis 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64458, updated on 5-Mar-2024

    Summary

    Official Symbol
    Scrg1provided by RGD
    Official Full Name
    stimulator of chondrogenesis 1provided by RGD
    Primary source
    RGD:68377
    See related
    Ensembl:ENSRNOG00000069516 AllianceGenome:RGD:68377
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in mesenchymal stem cell proliferation. Predicted to be located in cytoplasm. Predicted to be active in Golgi apparatus and neuron projection terminus. Orthologous to human SCRG1 (stimulator of chondrogenesis 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 183.2) See more
    Orthologs
    NEW
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    Genomic context

    Location:
    16p11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (37770739..37799010, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (32760028..32788299, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (36127536..36161041, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene high mobility group box 2 Neighboring gene Sin3A associated protein 30 Neighboring gene transfer RNA glutamic acid (anticodon UUC) 9 Neighboring gene uncharacterized LOC102548719 Neighboring gene uncharacterized LOC134482496

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in mesenchymal stem cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in neuron projection terminus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in neuron projection terminus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    scrapie-responsive protein 1
    Names
    scRG-1
    scrapie responsive gene 1
    scrapie-responsive gene 1 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033499.1NP_277034.1  scrapie-responsive protein 1 precursor

      See identical proteins and their annotated locations for NP_277034.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ132434
      UniProtKB/Swiss-Prot
      Q9Z0K6
      UniProtKB/TrEMBL
      A6KIV2
      Related
      ENSRNOP00000084059.1, ENSRNOT00000110541.1
      Conserved Domains (1) summary
      pfam15224
      Location:2297
      SCRG1; Scrapie-responsive protein 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      37770739..37799010 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)