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    Cep78 centrosomal protein 78 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 60347, updated on 30-Mar-2024

    Summary

    Official Symbol
    Cep78provided by RGD
    Official Full Name
    centrosomal protein 78provided by RGD
    Primary source
    RGD:620464
    See related
    Ensembl:ENSRNOG00000014041 AllianceGenome:RGD:620464
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ip63
    Summary
    Predicted to be involved in cilium organization. Predicted to be located in ciliary basal body. Predicted to be active in centrosome. Orthologous to human CEP78 (centrosomal protein 78). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 44.6), Thymus (RPKM 41.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Cep78 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (222674193..222702124, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (213246183..213275275, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (233185815..233214876, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene phosphoserine aminotransferase 1 Neighboring gene uncharacterized LOC102553402 Neighboring gene uncharacterized LOC134485208 Neighboring gene G protein subunit alpha q

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cilium organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    centrosomal protein of 78 kDa
    Names
    centrosomal protein 78kDa

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021741.2NP_068509.2  centrosomal protein of 78 kDa

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000001, X99330
      UniProtKB/TrEMBL
      A6I0H6, F1LP29
      Related
      ENSRNOP00000018951.5, ENSRNOT00000018951.7
      Conserved Domains (2) summary
      cd00116
      Location:113299
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cl09820
      Location:413485
      PhaP_Bmeg; Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      222674193..222702124 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006231136.5XP_006231198.1  centrosomal protein of 78 kDa isoform X1

      See identical proteins and their annotated locations for XP_006231198.1

      UniProtKB/TrEMBL
      A6I0H6, A6I0H7
      Conserved Domains (2) summary
      cd00116
      Location:113299
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cl09820
      Location:413485
      PhaP_Bmeg; Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg)
    2. XM_063272456.1XP_063128526.1  centrosomal protein of 78 kDa isoform X6

    3. XM_039088989.2XP_038944917.1  centrosomal protein of 78 kDa isoform X2

      UniProtKB/TrEMBL
      A6I0H6
      Conserved Domains (1) summary
      cl39015
      Location:23217
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    4. XM_039088994.2XP_038944922.1  centrosomal protein of 78 kDa isoform X5

      Conserved Domains (1) summary
      cl39015
      Location:113299
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    5. XM_039088993.2XP_038944921.1  centrosomal protein of 78 kDa isoform X4

      Conserved Domains (1) summary
      cl39015
      Location:113299
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    6. XM_039088991.2XP_038944919.1  centrosomal protein of 78 kDa isoform X3

      UniProtKB/TrEMBL
      A6I0H6
      Related
      ENSRNOP00000087144.1
      Conserved Domains (1) summary
      cl39015
      Location:23217
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...