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    Glyatl2 glycine-N-acyltransferase-like 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171179, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Glyatl2provided by RGD
    Official Full Name
    glycine-N-acyltransferase-like 2provided by RGD
    Primary source
    RGD:621231
    See related
    Ensembl:ENSRNOG00000012387 AllianceGenome:RGD:621231
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    HP33; Keg1
    Summary
    Predicted to enable N-acyltransferase activity. Colocalizes with centrosome. Orthologous to human GLYAT (glycine-N-acyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 741.8) and Liver (RPKM 562.8) See more
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    Genomic context

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    See Glyatl2 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (219232154..219265142)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (209807488..209840480)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (229519586..229552573)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily B member 95 like 1 Neighboring gene olfactory receptor family 5 subfamily B member 95 Neighboring gene ciliary neurotrophic factor Neighboring gene zinc finger protein 91 Neighboring gene leupaxin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. HP33: hepatocellular carcinoma-enriched 33-kDa protein with similarity to mitochondrial N-acyltransferase but localized in a microtubule-dependent manner at the centrosome. Nakadai T, et al. J Cell Sci, 1999 May. PMID 10194414
    2. Structure of rat gamma-tubulin and its binding to HP33. Nakadai T, et al. DNA Res, 1999 Jun 30. PMID 10470852
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables N-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gamma-tubulin binding NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables glycine N-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in centrosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    glycine N-acyltransferase-like protein Keg1
    Names
    Acyl-CoA:glycine N-acyltransferase protein Keg1
    glycine N-acyltransferase protein Keg1
    hepatocellular carcinoma-enriched protein of 33 kDa
    kidney expressed gene 1
    kidney-expressed gene 1 protein
    NP_599157.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134330.2 → NP_599157.2  glycine N-acyltransferase-like protein Keg1

      See identical proteins and their annotated locations for NP_599157.2

      Status: PROVISIONAL

      Source sequence(s)
      BC078701
      UniProtKB/Swiss-Prot
      Q68G42, Q9Z2Y0
      UniProtKB/TrEMBL
      A0A8I6A4V2, A6I0E6
      Related
      ENSRNOP00000016593.4, ENSRNOT00000016593.7
      Conserved Domains (2) summary
      pfam08444
      Location:206 → 294
      Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
      pfam06021
      Location:1 → 205
      Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      219232154..219265142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Z2Y0.2 GenPept UniProtKB/Swiss-Prot:Q9Z2Y0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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