Sdhaf1 succinate dehydrogenase complex assembly factor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Sdhaf1provided by RGD
Full Name: succinate dehydrogenase complex assembly factor 1provided by RGD
Primary source: RGD:1562079
See related: Ensembl:ENSRNOG00000047045 AllianceGenome:RGD:1562079
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Lyrm8; RGD1562079
Summary: Predicted to be involved in mitochondrial respiratory chain complex II assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex II deficiency. Orthologous to human SDHAF1 (succinate dehydrogenase complex assembly factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: 1q21

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (94703662..94704611, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (85576207..85577156, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (88779476..88780425, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH129537 (e-PCR)
- UniSTS:212839

RH129705 (e-PCR)
- UniSTS:212839

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in mitochondrial respiratory chain complex II assembly	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial respiratory chain complex II assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: succinate dehydrogenase assembly factor 1, mitochondrial

Names: LYR motif-containing protein 8; SDH assembly factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001177687.1 → NP_001171158.1 succinate dehydrogenase assembly factor 1, mitochondrial

See identical proteins and their annotated locations for NP_001171158.1

Status: PROVISIONAL

Source sequence(s)

BC159436

UniProtKB/Swiss-Prot

B0K036

Related

ENSRNOP00000067764.1, ENSRNOT00000074494.2

Conserved Domains (1) summary

cd20268
Location:5 → 63

Complex1_LYR_SDHAF1_LYRM8; LYR (leucine-tyrosine-arginine) motif found in mitochondrial succinate dehydrogenase assembly factor 1 (SDHAF1) and similar proteins