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    Xkr5 XK related 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 497083, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Xkr5provided by RGD
    Official Full Name
    XK related 5provided by RGD
    Primary source
    RGD:1359335
    See related
    Ensembl:ENSRNOG00000028636 AllianceGenome:RGD:1359335
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human XKR5 (XK related 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 32.1), Spleen (RPKM 16.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    16q12.5
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (77577387..77595377)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (70874983..70892972)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (75744786..75762694)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene defensin beta 40 Neighboring gene pyruvate kinase M1/2 like 1 Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 5 Neighboring gene microtubule-associated protein 1 light chain 3 beta 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    XK-related protein 5
    Names
    X Kell blood group precursor-related family, member 5
    X-linked Kx blood group related 5
    XK, Kell blood group complex subunit-related family, member 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396398.1 → NP_001383327.1  XK-related protein 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      F7F7I4
      Related
      ENSRNOP00000032580.5, ENSRNOT00000032368.6
      Conserved Domains (1) summary
      pfam09815
      Location:16 → 321
      XK-related; XK-related protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      77577387..77595377
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275627.1 → XP_063131697.1  XK-related protein 5 isoform X2

    2. XM_039094745.2 → XP_038950673.1  XK-related protein 5 isoform X1

      UniProtKB/TrEMBL
      Q5GH58
      Conserved Domains (1) summary
      pfam09815
      Location:18 → 234
      XK-related; XK-related protein

    3. XM_039094747.2 → XP_038950675.1  XK-related protein 5 isoform X1

      UniProtKB/TrEMBL
      Q5GH58
      Conserved Domains (1) summary
      pfam09815
      Location:18 → 234
      XK-related; XK-related protein

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001012228.1: Suppressed sequence

      Description
      NM_001012228.1: This RefSeq was removed because currently there is not sufficient data to support this transcript.
    Nucleotide Protein Strain
    Heading Accession and Version

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