Acrbp acrosin binding protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Acrbpprovided by RGD
Official Full Name: acrosin binding proteinprovided by RGD
Primary source: RGD:1564880
See related: Ensembl:ENSRNOG00000017399 AllianceGenome:RGD:1564880
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in acrosome assembly and fertilization. Predicted to be located in acrosomal membrane and extracellular region. Predicted to be active in acrosomal vesicle. Orthologous to human ACRBP (acrosin binding protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 222.8), Thymus (RPKM 34.2) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q42

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (159537395..159550454)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (157851149..157864211)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (157563990..157577045)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AU046982 (e-PCR)
- UniSTS:110957

RH127593 (e-PCR)
- UniSTS:210903

RH136757 (e-PCR)
- UniSTS:218846

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in acrosome assembly	IEA Inferred from Electronic Annotation more info
involved_in acrosome assembly	ISO Inferred from Sequence Orthology more info
involved_in acrosome assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in fertilization	IEA Inferred from Electronic Annotation more info
involved_in fertilization	ISO Inferred from Sequence Orthology more info
involved_in fertilization	ISS Inferred from Sequence or Structural Similarity more info
involved_in spermatid development	ISO Inferred from Sequence Orthology more info
involved_in spermatid development	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in acrosomal membrane	ISO Inferred from Sequence Orthology more info
located_in acrosomal membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in acrosomal vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in acrosomal vesicle	IEA Inferred from Electronic Annotation more info
located_in acrosomal vesicle	ISO Inferred from Sequence Orthology more info
located_in acrosomal vesicle	ISS Inferred from Sequence or Structural Similarity more info
located_in extracellular region	ISO Inferred from Sequence Orthology more info
located_in extracellular region	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: acrosin-binding protein

Names: acrosin-binding protein, 60 kDa form; proacrosin binding protein; proacrosin-binding protein sp32

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.