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    Fam193a family with sequence homology 193, member A [ Mus musculus (house mouse) ]

    Gene ID: 231128, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Fam193aprovided by MGI
    Official Full Name
    family with sequence homology 193, member Aprovided by MGI
    Primary source
    MGI:MGI:2447768
    See related
    Ensembl:ENSMUSG00000037210 AllianceGenome:MGI:2447768
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Orthologous to human FAM193A (family with sequence similarity 193 member A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 28.6), CNS E14 (RPKM 15.6) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam193a in Genome Data Viewer
    Location:
    5 B2; 5 17.88 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (34527295..34643800)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (34369933..34486458)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 99 Neighboring gene predicted gene 5553 Neighboring gene RIKEN cDNA A830049F12 gene Neighboring gene STARR-positive B cell enhancer ABC_E668 Neighboring gene ring finger protein 4 Neighboring gene STARR-positive B cell enhancer ABC_E6320 Neighboring gene predicted gene, 57744 Neighboring gene STARR-seq mESC enhancer starr_12839 Neighboring gene STARR-seq mESC enhancer starr_12841 Neighboring gene STARR-positive B cell enhancer ABC_E10314 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:34863580-34863766 Neighboring gene TNFAIP3 interacting protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E10315 Neighboring gene STARR-positive B cell enhancer ABC_E6321 Neighboring gene SH3-domain binding protein 2 Neighboring gene predicted gene, 22847

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. CHIP as a membrane-shuttling proteostasis sensor. Kopp Y, et al. Elife, 2017 Nov 1. PMID 29091030, Free PMC Article
    2. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
    3. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. Das R, et al. J Cell Sci, 2019 Jun 17. PMID 31138677, Free PMC Article
    4. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article
    5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Potential readthrough

    Included gene: Rnf4

    Homology

    Clone Names

    • MGC106708

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM193A
    Names
    family with sequence similarity 193, member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243123.2 → NP_001230052.1  protein FAM193A

      Status: VALIDATED

      Source sequence(s)
      AC102620
      UniProtKB/TrEMBL
      M0QWZ1
      Related
      ENSMUSP00000138082.2, ENSMUST00000180376.8
      Conserved Domains (3) summary
      pfam11679
      Location:941 → 1021
      DUF3275; Protein of unknown function (DUF3275)
      pfam13863
      Location:1104 → 1179
      DUF4200; Domain of unknown function (DUF4200)
      pfam15914
      Location:1462 → 1515
      FAM193_C; FAM193 family C-terminal

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      34527295..34643800
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001030306.1: Suppressed sequence

      Description
      NM_001030306.1: This RefSeq was permanently suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CGI1.2 GenPept UniProtKB/Swiss-Prot:Q8CGI1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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