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    Glb1l galactosidase, beta 1-like [ Mus musculus (house mouse) ]

    Gene ID: 74577, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Glb1lprovided by MGI
    Official Full Name
    galactosidase, beta 1-likeprovided by MGI
    Primary source
    MGI:MGI:1921827
    See related
    Ensembl:ENSMUSG00000026200 AllianceGenome:MGI:1921827
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4833408P15Rik
    Summary
    Predicted to enable beta-galactosidase activity. Predicted to be involved in carbohydrate metabolic process. Located in extracellular space. Orthologous to human GLB1L (galactosidase beta 1 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 25.0), kidney adult (RPKM 18.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    1 C4; 1 38.63 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (75174178..75187460, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (75196971..75210827, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family B member 6 Neighboring gene STARR-positive B cell enhancer ABC_E8982 Neighboring gene autophagy related 9A Neighboring gene STARR-positive B cell enhancer ABC_E321 Neighboring gene ankyrin repeat and zinc finger domain containing 1 Neighboring gene serine/threonine kinase 16 Neighboring gene STARR-positive B cell enhancer ABC_E3282 Neighboring gene tubulin, alpha 4A Neighboring gene RIKEN cDNA A630095N17 gene Neighboring gene STARR-seq mESC enhancer starr_01353

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Abonnenc M, et al. Circ Res, 2013 Oct 25. PMID 24006456
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables beta-galactosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular space HDA PubMed 
    is_active_in vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    beta-galactosidase-1-like protein
    NP_083286.1
    XP_006496616.1
    XP_006496617.1
    XP_006496618.1
    XP_011237015.1
    XP_017168026.1
    XP_030099073.1
    XP_036009894.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029010.2 → NP_083286.1  beta-galactosidase-1-like protein precursor

      See identical proteins and their annotated locations for NP_083286.1

      Status: VALIDATED

      Source sequence(s)
      AC166150
      Consensus CDS
      CCDS48291.1
      UniProtKB/Swiss-Prot
      Q8CDK6, Q8VC60, Q9D631
      UniProtKB/TrEMBL
      A0A087WPH5
      Related
      ENSMUSP00000109253.2, ENSMUST00000113623.8
      Conserved Domains (1) summary
      pfam01301
      Location:34 → 349
      Glyco_hydro_35; Glycosyl hydrolases family 35

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      75174178..75187460 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496554.5 → XP_006496617.1  beta-galactosidase-1-like protein isoform X1

      See identical proteins and their annotated locations for XP_006496617.1

      UniProtKB/Swiss-Prot
      Q8CDK6, Q8VC60, Q9D631
      UniProtKB/TrEMBL
      A0A087WPH5
      Conserved Domains (1) summary
      pfam01301
      Location:34 → 349
      Glyco_hydro_35; Glycosyl hydrolases family 35

    2. XM_011238713.4 → XP_011237015.1  beta-galactosidase-1-like protein isoform X2

      UniProtKB/TrEMBL
      A0A087WPH5
      Related
      ENSMUSP00000139780.2, ENSMUST00000186173.7
      Conserved Domains (1) summary
      cl38930
      Location:34 → 259
      AmyAc_family; Alpha amylase catalytic domain family

    3. XM_017312537.3 → XP_017168026.1  beta-galactosidase-1-like protein isoform X1

      UniProtKB/Swiss-Prot
      Q8CDK6, Q8VC60, Q9D631
      UniProtKB/TrEMBL
      A0A087WPH5
      Conserved Domains (1) summary
      pfam01301
      Location:34 → 349
      Glyco_hydro_35; Glycosyl hydrolases family 35

    4. XM_030243213.2 → XP_030099073.1  beta-galactosidase-1-like protein isoform X4

      Conserved Domains (1) summary
      cl38930
      Location:21 → 134
      AmyAc_family; Alpha amylase catalytic domain family

    5. XM_006496555.5 → XP_006496618.1  beta-galactosidase-1-like protein isoform X3

      Conserved Domains (1) summary
      cl38930
      Location:1 → 224
      AmyAc_family; Alpha amylase catalytic domain family

    6. XM_036154001.1 → XP_036009894.1  beta-galactosidase-1-like protein isoform X3

      Conserved Domains (1) summary
      cl38930
      Location:1 → 224
      AmyAc_family; Alpha amylase catalytic domain family

    7. XM_006496553.5 → XP_006496616.1  beta-galactosidase-1-like protein isoform X1

      See identical proteins and their annotated locations for XP_006496616.1

      UniProtKB/Swiss-Prot
      Q8CDK6, Q8VC60, Q9D631
      UniProtKB/TrEMBL
      A0A087WPH5
      Conserved Domains (1) summary
      pfam01301
      Location:34 → 349
      Glyco_hydro_35; Glycosyl hydrolases family 35

    RNA

    1. XR_003947211.2 RNA Sequence

    2. XR_373546.4 RNA Sequence

    3. XR_004934822.1 RNA Sequence

    4. XR_373547.4 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VC60.1 GenPept UniProtKB/Swiss-Prot:Q8VC60

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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