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    Mcrip2 MAPK regulated co-repressor interacting protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685545, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Mcrip2provided by RGD
    Official Full Name
    MAPK regulated co-repressor interacting protein 2provided by RGD
    Primary source
    RGD:1592603
    See related
    Ensembl:ENSRNOG00000020029 AllianceGenome:RGD:1592603
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam195a
    Summary
    Predicted to be located in cytoplasmic stress granule and nucleus. Orthologous to human MCRIP2 (MAPK regulated corepressor interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 297.9), Adrenal (RPKM 274.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    10q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15388325..15393302, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14883813..14888784, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15230801..15235740, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene rhomboid like 1 Neighboring gene ras homolog family member T2 Neighboring gene WD repeat domain 90 Neighboring gene methyltransferase like 26 Neighboring gene transfer RNA glycine (anticodon CCC) 5 Neighboring gene WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins. Bish R, et al. Biomolecules, 2015 Jul 15. PMID 26184334, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasmic stress granule ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    MAPK regulated corepressor interacting protein 2
    Names
    family with sequence similarity 195, member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109475.1 → NP_001102945.1  MAPK regulated corepressor interacting protein 2

      See identical proteins and their annotated locations for NP_001102945.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HD70, D3ZM07
      Related
      ENSRNOP00000027169.4, ENSRNOT00000027170.6
      Conserved Domains (1) summary
      pfam14799
      Location:61 → 157
      FAM195; FAM195 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15388325..15393302 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086832.2 → XP_038942760.1  MAPK regulated corepressor interacting protein 2 isoform X1

      Conserved Domains (1) summary
      pfam14799
      Location:61 → 137
      FAM195; FAM195 family

    2. XM_063269842.1 → XP_063125912.1  MAPK regulated corepressor interacting protein 2 isoform X3

    3. XM_063269841.1 → XP_063125911.1  MAPK regulated corepressor interacting protein 2 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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