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    Nrip3 nuclear receptor interacting protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 78593, updated on 12-Mar-2024

    Summary

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    Official Symbol
    Nrip3provided by MGI
    Official Full Name
    nuclear receptor interacting protein 3provided by MGI
    Primary source
    MGI:MGI:1925843
    See related
    Ensembl:ENSMUSG00000034825 AllianceGenome:MGI:1925843
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D7H11orf14; A330103B05Rik; ICRFP703B1614Q5.2
    Summary
    Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Is expressed in several structures, including alimentary system; nervous system; olfactory epithelium; retina layer; and vibrissa. Orthologous to human NRIP3 (nuclear receptor interacting protein 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in frontal lobe adult (RPKM 38.6), cerebellum adult (RPKM 13.0) and 2 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 E3; 7 57.49 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (109357263..109380752, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (109758056..109781545, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene basic transcription factor 3 pseudogene Neighboring gene TMEM9 domain family, member B Neighboring gene predicted gene, 22822 Neighboring gene signal peptide, CUB domain, EGF-like 2 Neighboring gene STARR-seq mESC enhancer starr_19808 Neighboring gene STARR-seq mESC enhancer starr_19809 Neighboring gene DENN domain containing 5A Neighboring gene STARR-seq mESC enhancer starr_19810

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis. Hung CH, et al. Int J Mol Sci, 2021 Jul 27. PMID 34360789, Free PMC Article
    2. Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. Amid C, et al. Cytogenet Cell Genet, 2001. PMID 11528127
    3. MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Kay JN, et al. Nature, 2012 Mar 11. PMID 22407321, Free PMC Article
    4. The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Schilling K, et al. Cerebellum, 2009 Dec. PMID 19554387
    5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins JR, et al. Science, 2010 Apr 30. PMID 20360068, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    nuclear receptor-interacting protein 3
    Names
    ICRFP703N2430Q5.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020610.1 → NP_065635.1  nuclear receptor-interacting protein 3

      See identical proteins and their annotated locations for NP_065635.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ400878
      Consensus CDS
      CCDS21739.1
      UniProtKB/Swiss-Prot
      Q8BUN8, Q9JJR9
      UniProtKB/TrEMBL
      Q6GQT2
      Related
      ENSMUSP00000033331.7, ENSMUST00000033331.7
      Conserved Domains (1) summary
      cd05480
      Location:109 → 211
      NRIP_C; NRIP_C; putative nuclear receptor interacting protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      109357263..109380752 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9JJR9.1 GenPept UniProtKB/Swiss-Prot:Q9JJR9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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