Wipf2 WAS/WASL interacting protein family, member 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Wipf2provided by MGI
Official Full Name: WAS/WASL interacting protein family, member 2provided by MGI
Primary source: MGI:MGI:1924462
See related: Ensembl:ENSMUSG00000038013 AllianceGenome:MGI:1924462
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Wich; Wire; Gm1176; 1110014J05Rik; 5730509C05Rik
Summary: Predicted to enable actin binding activity. Predicted to be involved in actin filament-based movement. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be active in actin filament. Orthologous to human WIPF2 (WAS/WASL interacting protein family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in bladder adult (RPKM 5.6), cortex adult (RPKM 4.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 D; 11 62.71 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (98754424..98796404)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (98863598..98905578)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH124605 (e-PCR)
- UniSTS:161427

RH125693 (e-PCR)
- UniSTS:162466

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: WAS/WASL-interacting protein family member 2

Names: WASP-binding protein; WASP-interacting protein-related protein; WIP-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_197940.2 → NP_922922.1 WAS/WASL-interacting protein family member 2

See identical proteins and their annotated locations for NP_922922.1

Status: VALIDATED

Source sequence(s)

AL591067

Consensus CDS

CCDS25366.1

UniProtKB/Swiss-Prot

Q6PEV3

Related

ENSMUSP00000046991.9, ENSMUST00000037480.9

Conserved Domains (3) summary

PRK12323
Location:60 → 220

PRK12323; DNA polymerase III subunit gamma/tau

cd21762
Location:50 → 53

WH2; actin-binding sequence [structural motif]

cl41728
Location:33 → 62

WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins