Cst9l cystatin 9-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cst9lprovided by RGD
Official Full Name: cystatin 9-likeprovided by RGD
Primary source: RGD:1311032
See related: Ensembl:ENSRNOG00000005162 AllianceGenome:RGD:1311032
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Cst9
Summary: Predicted to enable cysteine-type endopeptidase inhibitor activity. Predicted to be involved in antimicrobial humoral response. Predicted to be active in extracellular space. Orthologous to several human genes including CST9L (cystatin 9 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward (RPKM 235.0) See more
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Genomic context

Location:: 3q41

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (156741232..156744045)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (136288093..136290906)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (143172691..143175504)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables cysteine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in antimicrobial humoral response	IBA Inferred from Biological aspect of Ancestor more info
involved_in antimicrobial humoral response	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cystatin 9-like

Names: cystatin 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001108597.1 → NP_001102067.1 cystatin 9-like precursor

See identical proteins and their annotated locations for NP_001102067.1

Status: PROVISIONAL

Source sequence(s)

CH474026

UniProtKB/TrEMBL

A6K7D7, D3ZMS9

Related

ENSRNOP00000006869.4, ENSRNOT00000006869.7

Conserved Domains (1) summary

cl09238
Location:43 → 136

CY; Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.