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    Mast4 microtubule associated serine/threonine kinase family member 4 [ Mus musculus (house mouse) ]

    Gene ID: 328329, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Mast4provided by MGI
    Official Full Name
    microtubule associated serine/threonine kinase family member 4provided by MGI
    Primary source
    MGI:MGI:1918885
    See related
    Ensembl:ENSMUSG00000034751 AllianceGenome:MGI:1918885
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0303; 4930420O11Rik
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cytoskeleton organization; intracellular signal transduction; and peptidyl-serine phosphorylation. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytoplasm. Is expressed in brain; thymus primordium; and ventral grey horn. Orthologous to human MAST4 (microtubule associated serine/threonine kinase family member 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 6.5), bladder adult (RPKM 6.3) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    13 D1; 13 54.94 cM
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (102868996..103471607, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (102732486..103335099, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr13:103468634-103468935 Neighboring gene STARR-positive B cell enhancer ABC_E7271 Neighboring gene STARR-positive B cell enhancer ABC_E1887 Neighboring gene STARR-positive B cell enhancer ABC_E7272 Neighboring gene STARR-positive B cell enhancer ABC_E10811 Neighboring gene STARR-seq mESC enhancer starr_35508 Neighboring gene predicted gene, 41046 Neighboring gene STARR-seq mESC enhancer starr_35509 Neighboring gene STARR-positive B cell enhancer ABC_E3097 Neighboring gene RIKEN cDNA 1700099I09 gene Neighboring gene CD180 antigen Neighboring gene predicted gene 17160 Neighboring gene STARR-seq mESC enhancer starr_35511 Neighboring gene STARR-seq mESC enhancer starr_35515 Neighboring gene STARR-positive B cell enhancer ABC_E3098 Neighboring gene predicted gene, 30106 Neighboring gene predicted gene, 30050 Neighboring gene fibrillarin pseudogene Neighboring gene STARR-seq mESC enhancer starr_35516 Neighboring gene STARR-seq mESC enhancer starr_35518 Neighboring gene STARR-seq mESC enhancer starr_35519 Neighboring gene predicted gene 5454 Neighboring gene ribosomal protein L21 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. MAST4 controls cell cycle in spermatogonial stem cells. Lee SJ, et al. Cell Prolif, 2023 Apr. PMID 36592615, Free PMC Article
    2. Mast4 determines the cell fate of MSCs for bone and cartilage development. Kim P, et al. Nat Commun, 2022 Jul 8. PMID 35803931, Free PMC Article
    3. Cloning of the genes encoding two murine and human cochlear unconventional type I myosins. Crozet F, et al. Genomics, 1997 Mar 1. PMID 9119401
    4. Analysis of Presenilin 1 and 2 interacting proteins in mouse cerebral cortex during development. Kumar A, et al. Int J Dev Neurosci, 2014 Nov. PMID 25196998
    5. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MAST4 controls cell cycle in spermatogonial stem cells.
      Title: MAST4 controls cell cycle in spermatogonial stem cells.
    2. Mast4 determines the cell fate of MSCs for bone and cartilage development.
      Title: Mast4 determines the cell fate of MSCs for bone and cartilage development.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (1)  1 citation

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    microtubule-associated serine/threonine-protein kinase 4
    NP_780380.2
    XP_006517764.1
    XP_006517765.1
    XP_006517766.1
    XP_006517767.1
    XP_006517768.1
    XP_006517769.1
    XP_006517770.1
    XP_011242974.1
    XP_011242975.1
    XP_011242976.1
    XP_017171016.1
    XP_017171017.1
    XP_017171018.1
    XP_017171019.1
    XP_017171020.1
    XP_017171021.1
    XP_030103167.1
    XP_030103168.1
    XP_030103169.1
    XP_030103170.1
    XP_036013969.1
    XP_036013970.1
    XP_036013971.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175171.3 → NP_780380.2  microtubule-associated serine/threonine-protein kinase 4

      See identical proteins and their annotated locations for NP_780380.2

      Status: VALIDATED

      Source sequence(s)
      AC112791, AC114827, AC124387, AC165290, AC167975, AC239606
      Consensus CDS
      CCDS49349.1
      UniProtKB/Swiss-Prot
      E9QAH7, Q3UVE7, Q62489, Q6ZQE0, Q811L6, Q8BME3
      Related
      ENSMUSP00000128464.2, ENSMUST00000167058.8
      Conserved Domains (4) summary
      smart00220
      Location:568 → 841
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00992
      Location:1144 → 1222
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:567 → 846
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:256 → 529
      DUF1908; Domain of unknown function (DUF1908)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      102868996..103471607 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315531.2 → XP_017171020.1  microtubule-associated serine/threonine-protein kinase 4 isoform X5

      Conserved Domains (3) summary
      cd00992
      Location:1147 → 1225
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:570 → 849
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:256 → 532
      DUF1908; Domain of unknown function (DUF1908)

    2. XM_017315530.2 → XP_017171019.1  microtubule-associated serine/threonine-protein kinase 4 isoform X4

      Conserved Domains (3) summary
      cd00992
      Location:1159 → 1237
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:582 → 861
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:268 → 544
      DUF1908; Domain of unknown function (DUF1908)

    3. XM_017315529.2 → XP_017171018.1  microtubule-associated serine/threonine-protein kinase 4 isoform X3

      Conserved Domains (3) summary
      cd00992
      Location:1172 → 1250
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:595 → 874
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:281 → 557
      DUF1908; Domain of unknown function (DUF1908)

    4. XM_017315528.2 → XP_017171017.1  microtubule-associated serine/threonine-protein kinase 4 isoform X2

      Conserved Domains (3) summary
      cd00992
      Location:1181 → 1259
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:604 → 883
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:293 → 566
      DUF1908; Domain of unknown function (DUF1908)

    5. XM_017315532.2 → XP_017171021.1  microtubule-associated serine/threonine-protein kinase 4 isoform X6

      Conserved Domains (3) summary
      cd00992
      Location:1117 → 1195
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:607 → 886
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:293 → 569
      DUF1908; Domain of unknown function (DUF1908)

    6. XM_017315527.2 → XP_017171016.1  microtubule-associated serine/threonine-protein kinase 4 isoform X1

      Conserved Domains (3) summary
      cd00992
      Location:1184 → 1262
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:607 → 886
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:293 → 569
      DUF1908; Domain of unknown function (DUF1908)

    7. XM_036158077.1 → XP_036013970.1  microtubule-associated serine/threonine-protein kinase 4 isoform X22

      Conserved Domains (3) summary
      cd00992
      Location:878 → 956
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:368 → 647
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:57 → 330
      DUF1908; Domain of unknown function (DUF1908)

    8. XM_006517705.5 → XP_006517768.1  microtubule-associated serine/threonine-protein kinase 4 isoform X17

      Conserved Domains (3) summary
      cd00992
      Location:945 → 1023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:368 → 647
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:57 → 330
      DUF1908; Domain of unknown function (DUF1908)

    9. XM_006517704.5 → XP_006517767.1  microtubule-associated serine/threonine-protein kinase 4 isoform X16

      Conserved Domains (3) summary
      cd00992
      Location:948 → 1026
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:371 → 650
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:57 → 333
      DUF1908; Domain of unknown function (DUF1908)

    10. XM_030247309.2 → XP_030103169.1  microtubule-associated serine/threonine-protein kinase 4 isoform X13

      UniProtKB/TrEMBL
      A0A0A6YXG1
      Related
      ENSMUSP00000141977.3, ENSMUST00000194446.7
      Conserved Domains (3) summary
      cd00992
      Location:957 → 1035
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:380 → 659
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:69 → 342
      DUF1908; Domain of unknown function (DUF1908)

    11. XM_006517702.5 → XP_006517765.1  microtubule-associated serine/threonine-protein kinase 4 isoform X12

      Conserved Domains (3) summary
      cd00992
      Location:960 → 1038
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:383 → 662
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:69 → 345
      DUF1908; Domain of unknown function (DUF1908)

    12. XM_030247307.2 → XP_030103167.1  microtubule-associated serine/threonine-protein kinase 4 isoform X9

      UniProtKB/TrEMBL
      A0A668KMA1
      Related
      ENSMUSP00000159269.2, ENSMUST00000239261.2
      Conserved Domains (3) summary
      cd00992
      Location:970 → 1048
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:393 → 672
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:82 → 355
      DUF1908; Domain of unknown function (DUF1908)

    13. XM_036158076.1 → XP_036013969.1  microtubule-associated serine/threonine-protein kinase 4 isoform X8

      Conserved Domains (3) summary
      cd00992
      Location:973 → 1051
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:396 → 675
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:82 → 358
      DUF1908; Domain of unknown function (DUF1908)

    14. XM_006517701.5 → XP_006517764.1  microtubule-associated serine/threonine-protein kinase 4 isoform X7

      Conserved Domains (3) summary
      cd00992
      Location:985 → 1063
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:408 → 687
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:94 → 370
      DUF1908; Domain of unknown function (DUF1908)

    15. XM_006517706.4 → XP_006517769.1  microtubule-associated serine/threonine-protein kinase 4 isoform X18

      Conserved Domains (3) summary
      cd00992
      Location:940 → 1018
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:363 → 642
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:49 → 325
      DUF1908; Domain of unknown function (DUF1908)

    16. XM_030247308.2 → XP_030103168.1  microtubule-associated serine/threonine-protein kinase 4 isoform X11

      Conserved Domains (3) summary
      cd00992
      Location:964 → 1042
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:387 → 666
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:76 → 349
      DUF1908; Domain of unknown function (DUF1908)

    17. XM_011244672.3 → XP_011242974.1  microtubule-associated serine/threonine-protein kinase 4 isoform X10

      UniProtKB/TrEMBL
      E9QPR4
      Related
      ENSMUSP00000096808.4, ENSMUST00000099202.10
      Conserved Domains (3) summary
      cd00992
      Location:967 → 1045
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:390 → 669
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:76 → 352
      DUF1908; Domain of unknown function (DUF1908)

    18. XM_030247310.2 → XP_030103170.1  microtubule-associated serine/threonine-protein kinase 4 isoform X19

      Conserved Domains (3) summary
      cd00992
      Location:937 → 1015
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:360 → 639
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:49 → 322
      DUF1908; Domain of unknown function (DUF1908)

    19. XM_011244673.4 → XP_011242975.1  microtubule-associated serine/threonine-protein kinase 4 isoform X15

      UniProtKB/TrEMBL
      E9PWX8
      Related
      ENSMUSP00000131651.2, ENSMUST00000171791.8
      Conserved Domains (3) summary
      cd00992
      Location:952 → 1030
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:375 → 654
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:64 → 337
      DUF1908; Domain of unknown function (DUF1908)

    20. XM_006517703.5 → XP_006517766.1  microtubule-associated serine/threonine-protein kinase 4 isoform X14

      Conserved Domains (3) summary
      cd00992
      Location:955 → 1033
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:378 → 657
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:64 → 340
      DUF1908; Domain of unknown function (DUF1908)

    21. XM_011244674.4 → XP_011242976.1  microtubule-associated serine/threonine-protein kinase 4 isoform X21

      Conserved Domains (3) summary
      cd00992
      Location:885 → 963
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:375 → 654
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:64 → 337
      DUF1908; Domain of unknown function (DUF1908)

    22. XM_036158078.1 → XP_036013971.1  microtubule-associated serine/threonine-protein kinase 4 isoform X23

      Conserved Domains (3) summary
      cd00992
      Location:798 → 876
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:221 → 500
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:1 → 183
      DUF1908; Domain of unknown function (DUF1908)

    23. XM_006517707.4 → XP_006517770.1  microtubule-associated serine/threonine-protein kinase 4 isoform X20

      Conserved Domains (3) summary
      cd00992
      Location:937 → 1015
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:360 → 639
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:46 → 322
      DUF1908; Domain of unknown function (DUF1908)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q811L6.3 GenPept UniProtKB/Swiss-Prot:Q811L6

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