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    pvalb1 parvalbumin 1 [ Danio rerio (zebrafish) ]

    Gene ID: 402805, updated on 27-Mar-2024

    Summary

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    Official Symbol
    pvalb1provided by ZNC
    Official Full Name
    parvalbumin 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-57
    See related
    Ensembl:ENSDARG00000037789 AllianceGenome:ZFIN:ZDB-GENE-040625-57
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:86939
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be active in cytoplasm and nucleus. Is expressed in musculature system and myotome. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See pvalb1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (61193890..61205783, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (60961302..60973150, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene parvalbumin 8 Neighboring gene parvalbumin 4 Neighboring gene parvalbumin 5 Neighboring gene lemur tyrosine kinase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Parvalbumin isoforms in zebrafish. Friedberg F. Mol Biol Rep, 2005 Sep. PMID 16172917
    2. The α2Na+/K+-ATPase is critical for skeletal and heart muscle function in zebrafish. Doganli C, et al. J Cell Sci, 2012 Dec 15. PMID 23097043
    3. Transcriptomes of post-mitotic neurons identify the usage of alternative pathways during adult and embryonic neuronal differentiation. Tallafuss A, et al. BMC Genomics, 2015 Dec 23. PMID 26699284, Free PMC Article
    4. Serial analysis of gene expression in the skeletal muscles of zebrafish fed with a methylmercury-contaminated diet. Cambier S, et al. Environ Sci Technol, 2010 Jan 1. PMID 20039754
    5. Expression profiling of zebrafish sox9 mutants reveals that Sox9 is required for retinal differentiation. Yokoi H, et al. Dev Biol, 2009 May 1. PMID 19210963, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    parvalbumin 1; parvalbumin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205572.2 → NP_991135.1  parvalbumin 1

      See identical proteins and their annotated locations for NP_991135.1

      Status: VALIDATED

      Source sequence(s)
      CR352263
      UniProtKB/TrEMBL
      A0A0R4INM7, A0A8N7XJB0, Q6IQ58, Q804W0
      Related
      ENSDARP00000137870.2, ENSDART00000171787.2
      Conserved Domains (2) summary
      cd00051
      Location:43 → 108
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:44 → 107
      EF-hand_7; EF-hand domain pair

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      61193890..61205783 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005164288.3 → XP_005164345.1  parvalbumin isoform X1

      UniProtKB/TrEMBL
      Q804W0
      Related
      ENSDARP00000055061.3, ENSDART00000055062.5
      Conserved Domains (2) summary
      cd00051
      Location:43 → 108
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:44 → 107
      EF-hand_7; EF-hand domain pair
    Nucleotide Protein Strain
    Heading Accession and Version

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