Cog3 component of oligomeric golgi complex 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cog3provided by RGD
Official Full Name: component of oligomeric golgi complex 3provided by RGD
Primary source: RGD:1304555
See related: Ensembl:ENSRNOG00000000155 AllianceGenome:RGD:1304555
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in several processes, including Golgi vesicle transport; protein glycosylation; and protein stabilization. Predicted to be located in Golgi apparatus; cytosol; and plasma membrane. Predicted to be part of Golgi transport complex. Orthologous to human COG3 (component of oligomeric golgi complex 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Lung (RPKM 99.4), Adrenal (RPKM 98.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 15q11

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (57389994..57480454, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (51020808..51071288, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (57753814..57805627, complement)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in Golgi organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in Golgi organization	ISO Inferred from Sequence Orthology more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	ISO Inferred from Sequence Orthology more info
involved_in glycosylation	ISO Inferred from Sequence Orthology more info
involved_in intra-Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intra-Golgi vesicle-mediated transport	ISO Inferred from Sequence Orthology more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in protein glycosylation	ISO Inferred from Sequence Orthology more info
involved_in protein localization to organelle	ISO Inferred from Sequence Orthology more info
involved_in protein stabilization	ISO Inferred from Sequence Orthology more info
involved_in retrograde transport, vesicle recycling within Golgi	ISO Inferred from Sequence Orthology more info
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
part_of Golgi transport complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Golgi transport complex	ISO Inferred from Sequence Orthology more info
located_in cis-Golgi network	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: conserved oligomeric Golgi complex subunit 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012157.1 → NP_001012157.1 conserved oligomeric Golgi complex subunit 3

See identical proteins and their annotated locations for NP_001012157.1

Status: PROVISIONAL

Source sequence(s)

BC083901

UniProtKB/TrEMBL

A0A8I6ABS2, F1LLY2, Q5XHZ8

Related

ENSRNOP00000000168.6, ENSRNOT00000000168.7

Conserved Domains (1) summary

pfam04136
Location:131 → 274

Sec34; Sec34-like family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086033.1 Reference GRCr8

Range

57389994..57480454 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063274435.1 → XP_063130505.1 conserved oligomeric Golgi complex subunit 3 isoform X2

UniProtKB/TrEMBL

A0A8I6ABS2
XM_063274434.1 → XP_063130504.1 conserved oligomeric Golgi complex subunit 3 isoform X1

UniProtKB/TrEMBL

A0A8I6GJ60
XM_063274437.1 → XP_063130507.1 conserved oligomeric Golgi complex subunit 3 isoform X3

UniProtKB/TrEMBL

A6HTT4