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    Ddit4l DNA-damage-inducible transcript 4-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100363484, updated on 13-Apr-2024

    Summary

    Official Symbol
    Ddit4lprovided by RGD
    Official Full Name
    DNA-damage-inducible transcript 4-likeprovided by RGD
    Primary source
    RGD:2322961
    See related
    Ensembl:ENSRNOG00000010047 AllianceGenome:RGD:2322961
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of signal transduction. Predicted to be located in cytoplasm. Orthologous to human DDIT4L (DNA damage inducible transcript 4 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 716.0), Heart (RPKM 122.6) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Ddit4l in Genome Data Viewer
    Location:
    2q43
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (228800831..228804478)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (226128273..226131044)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (242882219..242885088)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene endomucin Neighboring gene uncharacterized LOC120100949 Neighboring gene uncharacterized LOC134485976 Neighboring gene uncharacterized LOC134485977 Neighboring gene uncharacterized LOC108350121

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    DNA damage-inducible transcript 4-like protein
    Names
    DNA-damage-inducible transcript 4-like protein-like
    soleus muscle atrophied after hindlimb suspension protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001389274.1NP_001376203.1  DNA damage-inducible transcript 4-like protein

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      Q8VD50
      UniProtKB/TrEMBL
      A6HW05
      Related
      ENSRNOP00000013661.2, ENSRNOT00000013661.5
      Conserved Domains (1) summary
      pfam07809
      Location:65183
      RTP801_C; RTP801 C-terminal region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      228800831..228804478
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281093.1XP_063137163.1  DNA damage-inducible transcript 4-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZMJ4