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    Spata21 spermatogenesis associated 21 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366491, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Spata21provided by RGD
    Official Full Name
    spermatogenesis associated 21provided by RGD
    Primary source
    RGD:1302954
    See related
    Ensembl:ENSRNOG00000009058 AllianceGenome:RGD:1302954
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Spergen3
    Summary
    Predicted to enable calcium ion binding activity. Orthologous to human SPATA21 (spermatogenesis associated 21). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 192.8), Muscle (RPKM 41.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    5q36
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (158676224..158701567)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (153393309..153419430)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (159612541..159638073)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S21, pseudogene 1 Neighboring gene U6 spliceosomal RNA Neighboring gene SUZ RNA binding domain containing 1 Neighboring gene uncharacterized LOC134487027

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of rat Spergen-3, a spermatogenic cell-specific gene-3, encoding a novel 75-kDa protein bearing EF-hand motifs. Iida H, et al. J Androl, 2004 Nov-Dec. PMID 15477360
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Potential role of Spergen-3, a new member of EF-hand family, in differentiation of haploid spermatids in testis.
      Title: Molecular cloning of rat Spergen-3, a spermatogenic cell-specific gene-3, encoding a novel 75-kDa protein bearing EF-hand motifs.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC105642

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    spermatogenesis-associated protein 21
    Names
    spergen-3
    spermatogenic cell-specific gene 3 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004447.1 → NP_001004447.1  spermatogenesis-associated protein 21

      See identical proteins and their annotated locations for NP_001004447.1

      Status: PROVISIONAL

      Source sequence(s)
      AB168097
      UniProtKB/Swiss-Prot
      Q68A65
      Related
      ENSRNOP00000012147.3, ENSRNOT00000012147.5
      Conserved Domains (2) summary
      PHA03247
      Location:36 → 397
      PHA03247; large tegument protein UL36; Provisional
      cd00051
      Location:439 → 498
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      158676224..158701567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063288126.1 → XP_063144196.1  spermatogenesis-associated protein 21 isoform X1

      UniProtKB/Swiss-Prot
      Q68A65

    2. XM_063288128.1 → XP_063144198.1  spermatogenesis-associated protein 21 isoform X1

      UniProtKB/Swiss-Prot
      Q68A65

    3. XM_063288132.1 → XP_063144202.1  spermatogenesis-associated protein 21 isoform X3

    4. XM_063288130.1 → XP_063144200.1  spermatogenesis-associated protein 21 isoform X2

    5. XM_063288125.1 → XP_063144195.1  spermatogenesis-associated protein 21 isoform X1

      UniProtKB/Swiss-Prot
      Q68A65

    6. XM_063288131.1 → XP_063144201.1  spermatogenesis-associated protein 21 isoform X2

    7. XM_063288127.1 → XP_063144197.1  spermatogenesis-associated protein 21 isoform X1

      UniProtKB/Swiss-Prot
      Q68A65

    8. XM_063288129.1 → XP_063144199.1  spermatogenesis-associated protein 21 isoform X1

      UniProtKB/Swiss-Prot
      Q68A65
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q68A65.1 GenPept UniProtKB/Swiss-Prot:Q68A65

    Gene LinkOut

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