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    BomBc1 Bomanin Bicipital 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37099, updated on 10-May-2024

    Summary

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    Official Symbol
    BomBc1provided by FlyBase
    Official Full Name
    Bomanin Bicipital 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0034328
    Locus tag
    Dmel_CG15066
    See related
    AllianceGenome:FB:FBgn0034328
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH67033; Bom23; CG15066; DIM 23; DIM-23; Dmel\CG15066; IM23
    Summary
    Involved in antibacterial humoral response and defense response to Gram-positive bacterium. Located in extracellular region. Is expressed in photoreceptor cell. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See BomBc1 in Genome Data Viewer
    Location:
    55C4-55C4; 2-85 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18382704..18383235, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14270209..14270740, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR42736 Neighboring gene Bomanin Tailed 1 Neighboring gene Bomanin Short 1 Neighboring gene Bomanin Short 4 Neighboring gene Bomanin Bicipital 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Trans-regulatory changes underpin the evolution of the Drosophila immune response. Ding SD, et al. PLoS Genet, 2022 Nov. PMID 36342922, Free PMC Article
    2. The Putzig-NURF nucleosome remodeling complex is required for ecdysone receptor signaling and innate immunity in Drosophila melanogaster. Kugler SJ, et al. Genetics, 2011 May. PMID 21385730, Free PMC Article
    3. The Genetic Basis of Natural Variation in Drosophila melanogaster Immune Defense against Enterococcus faecalis. Chapman JR, et al. Genes (Basel), 2020 Feb 22. PMID 32098395, Free PMC Article
    4. Salty dog, an SLC5 symporter, modulates Drosophila response to salt stress. Stergiopoulos K, et al. Physiol Genomics, 2009 Mar 3. PMID 19018044, Free PMC Article
    5. Larvae of Drosophila melanogaster exhibit transcriptional activation of immune response pathways and antimicrobial peptides during recovery from supercooling stress. Štětina T, et al. Insect Biochem Mol Biol, 2019 Feb. PMID 30660665

    See all (85) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in antibacterial humoral response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in defense response to Gram-positive bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to bacterium HEP PubMed 
    involved_in response to mycotoxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bomanin bicipital 1
    Names
    BomBc1-PA
    CG15066-PA
    Immune-induced peptide 23 precursor
    bomanin 23
    bomanin Bc1
    immune induced molecule 23

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18382704..18383235 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137474.5 → NP_611318.2  bomanin bicipital 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611318.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SY64, Q9V8F5
      UniProtKB/TrEMBL
      A0A1B2AJ76, A4VA55
      Related
      FBpp0085908
      Conserved Domains (1) summary
      pfam08194
      Location:1 → 33
      DIM; DIM protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V8F5.2 Q9V8F5

    Gene LinkOut

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