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    lectin-21Ca [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 53552, updated on 10-May-2024

    Summary

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    Official Symbol
    lectin-21Caprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040107
    Locus tag
    Dmel_CG2826
    See related
    AllianceGenome:FB:FBgn0040107
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AC 004573A; AC004573a; CG2826; Dmel\CG2826; Lectin-21Ca
    Summary
    Predicted to enable galactose binding activity. Involved in multicellular organism reproduction. Predicted to be located in extracellular region. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in 3MC syndrome 2. Orthologous to human COLEC11 (collectin subfamily member 11). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See lectin-21Ca in Genome Data Viewer
    Location:
    21E2-21E2; 2-1.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (624617..625556)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (624617..625556)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44797 Neighboring gene long non-coding RNA:CR44798 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45369

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Neighbourhood continuity is not required for correct testis gene expression in Drosophila. Meadows LA, et al. PLoS Biol, 2010 Nov 30. PMID 21151342, Free PMC Article
    2. Molecular evolution and population genetics of duplicated accessory gland protein genes in Drosophila. Holloway AK, et al. Mol Biol Evol, 2004 Sep. PMID 15215320
    3. Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity. Dodd RB, et al. Glycobiology, 2001 May. PMID 11425795
    4. Insect glycobiology: a lectin multigene family in Drosophila melanogaster. Theopold U, et al. Biochem Biophys Res Commun, 1999 Aug 11. PMID 10441526
    5. Comparative genomic analysis of C-type lectin-domain genes in seven holometabolous insect species. Lu Y, et al. Insect Biochem Mol Biol, 2020 Nov. PMID 32841718

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables galactose binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological process involved in interspecies interaction between organisms IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sexual reproduction IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    lectin-21Ca
    Names
    CG2826-PA
    Lectin21Ca
    lectin-21Ca-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      624617..625556
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144385.3 → NP_652642.2  lectin-21Ca [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652642.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3DNH5, Q9VPS2
      Conserved Domains (1) summary
      cd00037
      Location:158 → 265
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPS2 Q9VPS2

    Gene LinkOut

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