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    CG12567 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3355094, updated on 10-May-2024

    Summary

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    Official Symbol
    CG12567provided by FlyBase
    Primary source
    FLYBASE:FBgn0039958
    Locus tag
    Dmel_CG12567
    See related
    AllianceGenome:FB:FBgn0039958
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12567
    Summary
    Predicted to enable 8-oxo-dGDP phosphatase activity. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG12567 in Genome Data Viewer
    Location:
    40F7-40F7; 2-54 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (23161122..23174484, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2LHet NW_001848855.1 (19633..32995, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43242 Neighboring gene Spf45 Neighboring gene long non-coding RNA:CR44268 Neighboring gene long non-coding RNA:CR46450 Neighboring gene mir-2490 stem loop Neighboring gene long non-coding RNA:CR46253

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cytogenetic and molecular characterization of heterochromatin gene models in Drosophila melanogaster. Rossi F, et al. Genetics, 2007 Feb. PMID 17110485, Free PMC Article
    2. Comparative Genomic Analyses Provide New Insights into the Evolutionary Dynamics of Heterochromatin in Drosophila. Caizzi R, et al. PLoS Genet, 2016 Aug. PMID 27513559, Free PMC Article
    3. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article
    4. SUMO-Enriched Proteome for Drosophila Innate Immune Response. Handu M, et al. G3 (Bethesda), 2015 Aug 18. PMID 26290570, Free PMC Article
    5. circRNA biogenesis competes with pre-mRNA splicing. Ashwal-Fluss R, et al. Mol Cell, 2014 Oct 2. PMID 25242144

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 8-oxo-dGDP phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12567-PA
    CG12567-PC
    CG12567-PD
    CG12567-PE
    CG12567-PF
    CG12567-PG
    NP_001015383.3
    NP_001015384.1
    NP_001104331.1
    NP_001163833.1
    NP_001163834.1
    NP_001287633.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      23161122..23174484 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001015383.2 → NP_001015383.3  uncharacterized protein Dmel_CG12567, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015383.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5LJU4, Q8SZ06
      Conserved Domains (2) summary
      cd03676
      Location:98 → 275
      Nudix_hydrolase_3; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
      pfam15916
      Location:22 → 128
      DUF4743; Domain of unknown function (DUF4743)

    2. NM_001110861.3 → NP_001104331.1  uncharacterized protein Dmel_CG12567, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001104331.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8Y4U4
      Conserved Domains (1) summary
      pfam15916
      Location:11 → 64
      DUF4743; Domain of unknown function (DUF4743)

    3. NM_001015384.3 → NP_001015384.1  uncharacterized protein Dmel_CG12567, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015384.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7PLS1
      Conserved Domains (2) summary
      cd03676
      Location:106 → 283
      Nudix_hydrolase_3; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
      pfam15916
      Location:11 → 136
      DUF4743; Domain of unknown function (DUF4743)

    4. NM_001170363.2 → NP_001163834.1  uncharacterized protein Dmel_CG12567, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163834.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D2A6J3
      Conserved Domains (1) summary
      pfam15916
      Location:11 → 64
      DUF4743; Domain of unknown function (DUF4743)

    5. NM_001300704.1 → NP_001287633.1  uncharacterized protein Dmel_CG12567, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287633.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7PLS1
      Conserved Domains (2) summary
      cd03676
      Location:106 → 283
      Nudix_hydrolase_3; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
      pfam15916
      Location:11 → 136
      DUF4743; Domain of unknown function (DUF4743)

    6. NM_001170362.1 → NP_001163833.1  uncharacterized protein Dmel_CG12567, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163833.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D2A6J2
      Conserved Domains (2) summary
      cd03676
      Location:92 → 269
      Nudix_hydrolase_3; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
      pfam15916
      Location:16 → 122
      DUF4743; Domain of unknown function (DUF4743)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8Y4U4 A8Y4U4
    D2A6J2 D2A6J2
    D2A6J3 D2A6J3
    Q7PLS1 Q7PLS1
    Q8SZ06 Q8SZ06

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