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    l(3)80Fg lethal (3) 80Fg [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3354941, updated on 10-May-2024

    Summary

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    Official Symbol
    l(3)80Fgprovided by FlyBase
    Official Full Name
    lethal (3) 80Fgprovided by FlyBase
    Primary source
    FLYBASE:FBgn0287183
    Locus tag
    Dmel_CG40178
    See related
    AllianceGenome:FB:FBgn0287183
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    80Fg; CG40178; Dmel\CG40178; l(3)Lh4A; l4A
    Summary
    Is expressed in adult head. Orthologous to human DNAJC16 (DnaJ heat shock protein family (Hsp40) member C16). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See l(3)80Fg in Genome Data Viewer
    Location:
    80F9-80F9; 3-47 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (25798441..26014112, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3LHet NW_001848857.1 (1181140..1396811, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45180 Neighboring gene Fatty acid synthase 3 Neighboring gene antisense RNA:CR45182 Neighboring gene pseudo Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic Analysis of the Heterochromatin of Chromosome 3 in Drosophila Melanogaster. II. Vital Loci Identified through Ems Mutagenesis. Marchant GE, et al. Genetics, 1988 Oct. PMID 17246481, Free PMC Article
    2. Cytogenetic analysis of the third chromosome heterochromatin of Drosophila melanogaster. Koryakov DE, et al. Genetics, 2002 Feb. PMID 11861557, Free PMC Article
    3. Cell-type specific features of circular RNA expression. Salzman J, et al. PLoS Genet, 2013. PMID 24039610, Free PMC Article
    4. Essential genes in proximal 3L heterochromatin of Drosophila melanogaster. Schulze S, et al. Mol Gen Genet, 2001 Feb. PMID 11254125
    5. Identification of regions interacting with ovoD mutations: potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster. Pauli D, et al. Genetics, 1995 Feb. PMID 7713427, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    mobile_element

    • Loc: c25805820-25804337 mobile_element_type = transposon:1360{}6377

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    lethal (3) 80Fg
    Names
    CG40178-PA
    CG40178-PB
    CG40178-PC
    l(3)80Fg-PA
    l(3)80Fg-PB
    l(3)80Fg-PC
    lethal 4A
    lethal4A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      25798441..26014112 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001015187.3 → NP_001015187.2  lethal (3) 80Fg, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015187.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BII3, Q6AWH1, Q7PLG1
      Conserved Domains (3) summary
      COG0484
      Location:30 → 94
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      cd02963
      Location:134 → 244
      TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...
      pfam00226
      Location:30 → 91
      DnaJ; DnaJ domain

    2. NM_001015188.4 → NP_001015188.2  lethal (3) 80Fg, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015188.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BII3, Q6AWH1, Q7PLG1
      Conserved Domains (3) summary
      COG0484
      Location:30 → 94
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      cd02963
      Location:134 → 244
      TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...
      pfam00226
      Location:30 → 91
      DnaJ; DnaJ domain

    3. NM_001276235.1 → NP_001263164.1  lethal (3) 80Fg, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263164.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BII3, Q6AWH1, Q7PLG1
      Conserved Domains (3) summary
      COG0484
      Location:30 → 94
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      cd02963
      Location:134 → 244
      TRX_DnaJ; TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40) ...
      pfam00226
      Location:30 → 91
      DnaJ; DnaJ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7PLG1 Q7PLG1

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